Histopathological and Serum Enzyme Changes of Propofol Combined with Pre-Anesthetic Agents in Domestic Pigeons (Columba livia)

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Mousavi Amirabbas; Abedi Gholamreza; Jahandideh Alireza; HESARAKI SAEED

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Journal: Iranian Journal of Veterinary Surgery Year:2019 | Volume:14 | Issue:2 (31) Page(s): 105-115

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Information Journal Paper

Title

Histopathological and Serum Enzyme Changes of Propofol Combined with Pre-Anesthetic Agents in Domestic Pigeons (Columba livia)

Author(s)

Mousavi Amirabbas | Abedi Gholamreza | Jahandideh Alireza | HESARAKI SAEED | Issue Writer Certificate

Keywords

MetamizoleQ1

PropofolQ2

MidazolamQ1

Pigeon anesthesiaQ1

PathologyQ1

Abstract

Objective-Because of the several differences between avian and mammalian physiology and anatomy, avian anesthesia requires to be more attentive. The aim of this study was to determine a safe injectable anesthetic agent that had more compatibility with the avian features. Design-Experimental study Animals-Twelve male pigeons Procedure-The pigeons weighing 302± 35 g (mean ± SD) were divided into two groups (n=6). In group 1, Midazolam (6 mg/kg,-IM) and in group 2, Metamizole (500 mg/kg,-IM) were administrated as the pre-anesthetic agents and thereafter, Propofol (8 mg/kg,-IV) was injected as the main anesthetic drug in both groups. The serum enzymatic changes were analyzed before and 1 hour after the last injection. Histopathological examinations of the liver and kidneys were also evaluated in terms of possible damages to the tissue. Results-The results of blood biochemistry evaluation in group 1 showed significant changes in the levels of AST and LDH before and after the injections (p<0. 05). HistoPathology results revealed significant changes in liver parameters in both groups. However, these changes were seen more prominent in group 1 (p<0. 05). Also, none of the drugs of both groups had a negative impact on the kidney tissue (p>0. 05). Conclusion and clinical relevance-Based on the results, Metamizole and Propofol combination showed that is safer than Midazolam and Propofol in terms of blood biochemical and histopathological evaluations and is more compatible with pigeons.

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APA: Copy

Mousavi, Amirabbas, Abedi, Gholamreza, Jahandideh, Alireza, & HESARAKI, SAEED. (2019). Histopathological and Serum Enzyme Changes of Propofol Combined with Pre-Anesthetic Agents in Domestic Pigeons (Columba livia). IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS), 14(2 (31) ), 105-115. SID. https://sid.ir/paper/135722/en

Vancouver: Copy

Mousavi Amirabbas, Abedi Gholamreza, Jahandideh Alireza, HESARAKI SAEED. Histopathological and Serum Enzyme Changes of Propofol Combined with Pre-Anesthetic Agents in Domestic Pigeons (Columba livia). IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS)[Internet]. 2019;14(2 (31) ):105-115. Available from: https://sid.ir/paper/135722/en

IEEE: Copy

Amirabbas Mousavi, Gholamreza Abedi, Alireza Jahandideh, and SAEED HESARAKI, “Histopathological and Serum Enzyme Changes of Propofol Combined with Pre-Anesthetic Agents in Domestic Pigeons (Columba livia),” IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS), vol. 14, no. 2 (31) , pp. 105–115, 2019, [Online]. Available: https://sid.ir/paper/135722/en

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