COMPARATIVE STUDY OF AMYLOIDOGENIC POTENTIAL OF AGNO3 AND FREUND'S ADJUVANT (AF) WITH THAT OF VITAMIN FREE CASEIN, ON SPATIO-TEMPORAL PATTERN OF EXPERIMENTAL AMYLOIDOSIS IN MICE

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JAMSHIDI KEYVAN; MOSHFEGHI SOGAND; MORTAZAVI P.; DANESHVAR A.R.; ABEDI MOHAMMAD

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Journal: JOURNAL OF VETERINARY MICROBIOLOGY Year:2009 | Volume:5 | Issue:1 Page(s): 67-71

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Title

COMPARATIVE STUDY OF AMYLOIDOGENIC POTENTIAL OF AGNO3 AND FREUND'S ADJUVANT (AF) WITH THAT OF VITAMIN FREE CASEIN, ON SPATIO-TEMPORAL PATTERN OF EXPERIMENTAL AMYLOIDOSIS IN MICE

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Keywords

AMYLOIDQ3

AGNO3Q3

FREUND'S ADJUVANTQ3

VITAMIN FREEQ3

MICEQ3

Abstract

Reactive AMYLOIDosis is a condition that complicates a long list of chronic inflammation, chronic infectious, malignant, and hereditary disorders. In the present study the potential effects of two AMYLOIDogenic substances: ie. AGNO3 and FREUND'S ADJUVANT (AF) with that of VITAMIN FREE casein, on spatio-temporal pattern of experimental AMYLOIDosis in MICE were compared. For this purpose a total of 40 male Swees MICE, obtained from Pasteur Institute Tehran, after being weighted were randomly divided into 4 groups including 2 treatments, 1 control (vitamin free casein) and 1 positive control (normal saline). At the end of 3rd, 5th and 7th weeks of experiment 3 MICE were randomly selected and euthnised. Spleen sample of each animal obtained and preserved in 10% neutral buffer formalin. Sample were then processed through different stages of dehydration, clearing and impregnation and finally embedded in paraffin blocks. Sections of 5µm thickness then cut and stained by alkaline Congo red techniques. Spleen weights and the data obtained from microscopic quantitative analysis did show no significant differences between groups A and B, A and C, and B and C. But significant differences were observed between groups A and D, B and D, and C and D respectively. It is concluded that two compounds ie; AGNO3 and FREUND'S ADJUVANT have the same potential, as does VITAMIN FREE casein have, in spatio-temporal pattern of experimental AMYLOIDosis in MICE.

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APA: Copy

JAMSHIDI, KEYVAN, MOSHFEGHI, SOGAND, MORTAZAVI, P., DANESHVAR, A.R., & ABEDI, MOHAMMAD. (2009). COMPARATIVE STUDY OF AMYLOIDOGENIC POTENTIAL OF AGNO3 AND FREUND'S ADJUVANT (AF) WITH THAT OF VITAMIN FREE CASEIN, ON SPATIO-TEMPORAL PATTERN OF EXPERIMENTAL AMYLOIDOSIS IN MICE. JOURNAL OF VETERINARY MICROBIOLOGY, 5(1), 67-71. SID. https://sid.ir/paper/152110/en

Vancouver: Copy

JAMSHIDI KEYVAN, MOSHFEGHI SOGAND, MORTAZAVI P., DANESHVAR A.R., ABEDI MOHAMMAD. COMPARATIVE STUDY OF AMYLOIDOGENIC POTENTIAL OF AGNO3 AND FREUND'S ADJUVANT (AF) WITH THAT OF VITAMIN FREE CASEIN, ON SPATIO-TEMPORAL PATTERN OF EXPERIMENTAL AMYLOIDOSIS IN MICE. JOURNAL OF VETERINARY MICROBIOLOGY[Internet]. 2009;5(1):67-71. Available from: https://sid.ir/paper/152110/en

IEEE: Copy

KEYVAN JAMSHIDI, SOGAND MOSHFEGHI, P. MORTAZAVI, A.R. DANESHVAR, and MOHAMMAD ABEDI, “COMPARATIVE STUDY OF AMYLOIDOGENIC POTENTIAL OF AGNO3 AND FREUND'S ADJUVANT (AF) WITH THAT OF VITAMIN FREE CASEIN, ON SPATIO-TEMPORAL PATTERN OF EXPERIMENTAL AMYLOIDOSIS IN MICE,” JOURNAL OF VETERINARY MICROBIOLOGY, vol. 5, no. 1, pp. 67–71, 2009, [Online]. Available: https://sid.ir/paper/152110/en

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