AN EXPERIMENTAL STUDY OF PROTECTIVE EFFECTS OF COMMERCIAL GARLIC EXTRACTS TABLETS CONSUMPTION ON CADMIUM CHLORIDE HEPATOTOXICITY IN RATS

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MOHAMMADI MALAYERI M.R.; SEDAGHAT R.; MOJARRAD O.; HEMMATI M.

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Paper Information

Journal: JOURNAL OF VETERINARY MICROBIOLOGY Year:2011 | Volume:7 | Issue:21 (SUPPLEMENTARY) Page(s): 1-6

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Title

AN EXPERIMENTAL STUDY OF PROTECTIVE EFFECTS OF COMMERCIAL GARLIC EXTRACTS TABLETS CONSUMPTION ON CADMIUM CHLORIDE HEPATOTOXICITY IN RATS

Author(s)

MOHAMMADI MALAYERI M.R. | SEDAGHAT R. | MOJARRAD O. | HEMMATI M. | Issue Writer Certificate

Keywords

HEPATOTOXICITYQ2

CADMIUMQ2

GARLIC EXTRACTQ2

HISTOPATHOLOGYQ2

Abstract

Cadmium is known as one of the most important environmental contaminants. It has many toxic effects on beings. The aim of this research was studying the role of one of the commercial garlic tablets in prevention of CADMIUM HEPATOTOXICITY in rats. For this purpose, 30 rats were randomly divided into five groups of six animals each. The study groups were designated as normal saline group, CADMIUM group (3 mg/kg), garlic group (100 mg/kg), CADMIUM (3 mg/kg) +garlic extract (50 mg/kg), and CADMIUM (3 mg/kg) +garlic extract (100 mg/kg). CADMIUM chloride was administered subcutaneously a dose per day although the mixture of GARLIC EXTRACT and corn oil was gavaged a dose per day. The study period continued for four weeks. The results revealed that serum ALT and AST increased in rats which received only CADMIUM chloride, whereas the GARLIC EXTRACT administration significantly decreased them in CADMIUM+garlic extract groups. Cellular swelling was the only obvious pathologic change in the livers which got toxic by CADMIUM. However, there were no obvious change in the livers of the rats that received preventive GARLIC EXTRACT doses. It was concluded that the commercial GARLIC EXTRACT tablet can prevent the hepatotoxic effects of CADMIUM chloride consumption.

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References

THE EFFECTS OF CADMIUM ON GROWTH PATTERN AND FEED CONVERSION RATE IN BROILER CHICKEN (ROSS BREED)

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APA: Copy

MOHAMMADI MALAYERI, M.R., SEDAGHAT, R., MOJARRAD, O., & HEMMATI, M.. (2011). AN EXPERIMENTAL STUDY OF PROTECTIVE EFFECTS OF COMMERCIAL GARLIC EXTRACTS TABLETS CONSUMPTION ON CADMIUM CHLORIDE HEPATOTOXICITY IN RATS. JOURNAL OF VETERINARY MICROBIOLOGY, 7(21 (SUPPLEMENTARY)), 1-6. SID. https://sid.ir/paper/152125/en

Vancouver: Copy

MOHAMMADI MALAYERI M.R., SEDAGHAT R., MOJARRAD O., HEMMATI M.. AN EXPERIMENTAL STUDY OF PROTECTIVE EFFECTS OF COMMERCIAL GARLIC EXTRACTS TABLETS CONSUMPTION ON CADMIUM CHLORIDE HEPATOTOXICITY IN RATS. JOURNAL OF VETERINARY MICROBIOLOGY[Internet]. 2011;7(21 (SUPPLEMENTARY)):1-6. Available from: https://sid.ir/paper/152125/en

IEEE: Copy

M.R. MOHAMMADI MALAYERI, R. SEDAGHAT, O. MOJARRAD, and M. HEMMATI, “AN EXPERIMENTAL STUDY OF PROTECTIVE EFFECTS OF COMMERCIAL GARLIC EXTRACTS TABLETS CONSUMPTION ON CADMIUM CHLORIDE HEPATOTOXICITY IN RATS,” JOURNAL OF VETERINARY MICROBIOLOGY, vol. 7, no. 21 (SUPPLEMENTARY), pp. 1–6, 2011, [Online]. Available: https://sid.ir/paper/152125/en

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