DETECTION OF GENE EXPRESSION AND SEQUENCE ANALYSIS OF CHICKEN CLASS II TRANS ACTIVATOR (CIITA)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHOSRAVI M.; NIKBAKHT GH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Veterinary Medicine Year:2013 | Volume:7 | Issue:4 Page(s): 287-292

Download Full-Text

Persian Verion

View:

479

Download:

125

Cites:

Information Journal Paper

Title

DETECTION OF GENE EXPRESSION AND SEQUENCE ANALYSIS OF CHICKEN CLASS II TRANS ACTIVATOR (CIITA)

Author(s)

KHOSRAVI M. | NIKBAKHT GH. | Issue Writer Certificate

Keywords

CHICKENQ1

CIITA GENE EXPRESSIONQ2

IMMUNITYQ2

Abstract

BACKGROUND: Class II transactivator (CIITA) is a dominant transcriptional element, controlling numerous genes in the immune system.CIITA is expressed in a constitutive pattern in antigen presenting cells although its expression can occur in other cell types. Since the revelation of CIITA, there have been considerable advances toward understanding its role as an activator of MHC II genes in humans and mice; nonetheless, there is a lack of published data for this gene in other animals such as CHICKENs.OBJECTIVES: The goals of this study were to determine the expression of class II transactivator (CIITA) in CHICKEN and analysis of the CIITA gene sequence between four Iranian indigenous CHICKEN ecotypes.METHODS: After securing the research accuracy and optimization of reaction conditions, cDNA and DNA samples of gene were obtained from four Iranian indigenous CHICKEN ecotypes. The PCR and RT-PCR products were sequenced and the data were analyzed by bioinformatics software.RESULTS: Comparison of the sequencing results with the reference sequence of the red jungle fowl revealed that these sequences belonged to the predicted CIIT Agene. There was a high conservation rate in the sequence of CIITA. CONCLUSIONS: Our results indicated that like other species, CIITA is transcripted in CHICKENs' immune system cells.Further studies on CHICKENs must be done to reveal CIITA roles in immune responses of CHICKENs.

Cites

No record.

References

No record.

Cite

APA: Copy

KHOSRAVI, M., & NIKBAKHT, GH.. (2013). DETECTION OF GENE EXPRESSION AND SEQUENCE ANALYSIS OF CHICKEN CLASS II TRANS ACTIVATOR (CIITA). IRANIAN JOURNAL OF VETERINARY MEDICINE (INTERNATIONAL JOURNAL OF VETERINARY RESEARCH), 7(4), 287-292. SID. https://sid.ir/paper/157900/en

Vancouver: Copy

KHOSRAVI M., NIKBAKHT GH.. DETECTION OF GENE EXPRESSION AND SEQUENCE ANALYSIS OF CHICKEN CLASS II TRANS ACTIVATOR (CIITA). IRANIAN JOURNAL OF VETERINARY MEDICINE (INTERNATIONAL JOURNAL OF VETERINARY RESEARCH)[Internet]. 2013;7(4):287-292. Available from: https://sid.ir/paper/157900/en

IEEE: Copy

M. KHOSRAVI, and GH. NIKBAKHT, “DETECTION OF GENE EXPRESSION AND SEQUENCE ANALYSIS OF CHICKEN CLASS II TRANS ACTIVATOR (CIITA),” IRANIAN JOURNAL OF VETERINARY MEDICINE (INTERNATIONAL JOURNAL OF VETERINARY RESEARCH), vol. 7, no. 4, pp. 287–292, 2013, [Online]. Available: https://sid.ir/paper/157900/en

Related Journal Papers