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Information Journal Paper

Title

Comparison and comparison of CD133 gene expression in healthy individuals and people with leukemia

Pages

  43-51

Abstract

 Aim & Background: CD133 is a membrane glycoprotein that contains 865 amino acids and is normally expressed in hematopoietic stem cells, endothelial precursor cells, neuronal and glial stem cells. The CD133 marker has been used to identify Cancer cells and many malignancies, including the brain, colon and lung. The aim of this study was to evaluate the expression level of CD133 as a marker for the detection of Leukemia. Materials and Methods: Blood samples were collected from 30 patients with Leukemia and 30 healthy controls. After RNA extraction, cDNA was synthesized and CD133 Gene expression was evaluated using Real-Time PCR technique. Data were analyzed using SPSS 16. 0 software. Results: According to the obtained data and statistical analysis (p <0. 05) using SPSS software, the expression level of CD133 Gene in Cancerous samples was significantly increased compared to healthy ones. That (p CD133 = 0. 0065) was obtained. Discussion and Conclusion: Given the role of CD133 as a marker for the identification of many Cancers, it can be concluded that CD133 can be a good marker for Cancer detection and prevention. Be Leukemia

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    APA: Copy

    Zamani Dehkordi, Narges, ZIA JAHROMI, NOOSHA, & Sazgar, Hosein. (2019). Comparison and comparison of CD133 gene expression in healthy individuals and people with leukemia. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 9(36 ), 43-51. SID. https://sid.ir/paper/204519/en

    Vancouver: Copy

    Zamani Dehkordi Narges, ZIA JAHROMI NOOSHA, Sazgar Hosein. Comparison and comparison of CD133 gene expression in healthy individuals and people with leukemia. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2019;9(36 ):43-51. Available from: https://sid.ir/paper/204519/en

    IEEE: Copy

    Narges Zamani Dehkordi, NOOSHA ZIA JAHROMI, and Hosein Sazgar, “Comparison and comparison of CD133 gene expression in healthy individuals and people with leukemia,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 9, no. 36 , pp. 43–51, 2019, [Online]. Available: https://sid.ir/paper/204519/en

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