THE EFFECT OF ASAFETIDA GUM EXTRACT ON BLOOD PARAMETERS AND HISTOPATHOLOGY OF TESTES IN MALE WISTAR RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AYOUBI A.; ARSHAMI J.; VALIZADEH R.; MOUSAVI Z.; MOUSAEI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Animal Science Research Year:2013 | Volume:4 | Issue:4 Page(s): 310-315

Download Full-Text

Persian Verion

View:

1,678

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF ASAFETIDA GUM EXTRACT ON BLOOD PARAMETERS AND HISTOPATHOLOGY OF TESTES IN MALE WISTAR RAT

Author(s)

Keywords

FERULA ASSA-FETIDAQ2

BLOOD PARAMETERSQ1

TESTOSTERONEQ3

HISTOPATHOLOGY OF TESTESQ3

WISTR RATQ2

Abstract

Ferula (Ferula assafetida) is a perennial plant which belongs to Umbellifere a family is grow in a wide range of arid and semi-arid regions in Iran.Ferulla assafetida contains compounds including coumarins and sesquiterpens that has been traditionally used to treat diseases such as nervous disorders, asthma, gastrointestinal disease and epilepsy.. Effects ofasafetida gum extract on BLOOD PARAMETERS and HISTOPATHOLOGY OF TESTES in male Wistar rat were studied using 32 rats with the initial body weight of 252 ± 4.3 g which randomly divided into 4 groups of 8 rats each the animals were injected with normal saline (control), and 75, 150 and 300 milligram per kilogram (mg/kg) body weight of asafetida gum extract respectively. The result showed that, 300mg/kg asafetida gum extract caused adverse effects on blood cholesterol, glucose, aspartate aminotransferase (AST) and alanine transaminase (ALT) concentration, while 75 mg/kg had positive effects on above-mentioned parameters. Serum TESTOSTERONE significantly decreased by increasing the level of asafetida gum extract and 300 mg/kg group had the lowest serum TESTOSTERONE concentration. The numbers of Leydig cell layers were suppressed in asafetida-treated animals in comparison with the control. In conclusion, therapeutic effects of asafetida gum extract are dose-dependent and the level 300 mg/kg caused adverse impacts on metabolites and reproductive performance in male Wistar rats. The refers morein vivo studies with bigger experiment population are required.

Cites

THE EFFECT OF WATER-ALCHOLIC EXTRACTED GUM OF FERULA ASAFOETIDA ON BODY AND TESTES WEIGHT, TESTOSTERONE AND SPERMATOGENESIS IN ADULT MALE WISTAR RAT

References

No record.

Cite

APA: Copy

AYOUBI, A., ARSHAMI, J., VALIZADEH, R., MOUSAVI, Z., & MOUSAEI, A.. (2013). THE EFFECT OF ASAFETIDA GUM EXTRACT ON BLOOD PARAMETERS AND HISTOPATHOLOGY OF TESTES IN MALE WISTAR RAT. IRANIAN JOURNAL OF ANIMAL SCIENCE RESEARCH, 4(4), 310-315. SID. https://sid.ir/paper/218283/en

Vancouver: Copy

AYOUBI A., ARSHAMI J., VALIZADEH R., MOUSAVI Z., MOUSAEI A.. THE EFFECT OF ASAFETIDA GUM EXTRACT ON BLOOD PARAMETERS AND HISTOPATHOLOGY OF TESTES IN MALE WISTAR RAT. IRANIAN JOURNAL OF ANIMAL SCIENCE RESEARCH[Internet]. 2013;4(4):310-315. Available from: https://sid.ir/paper/218283/en

IEEE: Copy

A. AYOUBI, J. ARSHAMI, R. VALIZADEH, Z. MOUSAVI, and A. MOUSAEI, “THE EFFECT OF ASAFETIDA GUM EXTRACT ON BLOOD PARAMETERS AND HISTOPATHOLOGY OF TESTES IN MALE WISTAR RAT,” IRANIAN JOURNAL OF ANIMAL SCIENCE RESEARCH, vol. 4, no. 4, pp. 310–315, 2013, [Online]. Available: https://sid.ir/paper/218283/en

Related Journal Papers