WHOLE-GENOME SCAN OF POPULATION DIFFERENTIATION IN ZEL AND LORI-BAKHTIARI SHEEP BREEDS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MORADI M.H.; NEJATI JAVAREMI A.; MORADI SHAHRBABAK M.; DODDS K.G.; MCEWAN J.C.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF AGRICULTURAL BIOTECHNOLOGY Year:2010 | Volume:2 | Issue:2 Page(s): 57-70

Download Full-Text

Persian Verion

View:

751

Download:

Cites:

Information Journal Paper

Title

WHOLE-GENOME SCAN OF POPULATION DIFFERENTIATION IN ZEL AND LORI-BAKHTIARI SHEEP BREEDS

Author(s)

Keywords

WHOLE-GENOME SCANQ3

POPULATION DIFFERENTIATIONQ3

SIGNATURES OF SELECTIONQ2

Abstract

Selection for increasing of frequency in new mutations that are advantageous only in a subset of populations leaves some signatures in the genome. Detecting these genomic regions is one of the most important areas of research in animal genetics since locations of selection signatures are often correlated with QTLs affecting economically important traits. In this paper, a whole genome scan using ~54000 SNP markers was performed in two main Iranian sheep breeds, namely Zel and Lori-Baktiari, with the aim of identifying divergently selected regions of the genome. Study of POPULATION DIFFERENTIATION across the genome using Weir and Cockerham’s FST test revealed some regions showing evidence of selection. In this paper, five regions which were in the 99.99 percentile of the genome distribution of FST scores were selected for further analysis.These regions were located in chromosomes 2, 5, 7 (two areas) and X. To evaluate the selection sweep, due to linkage disequilibrium, associated with these signatures we employed the Extended Haplotype Homozygosity (EHH) test. The results of this test as well as a study of haplotype bifurcation diagrams in these breeds also confirmed large allele differentiation in these regions.Finally, study of reported QTL regions in the orthologous areas of the cattle genome showed that they overlapped with the reported cattle QTLs, representing economically important traits such as carcass yield and reproductive traits. In conclusion, the results from this study provide one of the first attempts to develop a genome-wide map of selection footprints in the sheep genome and may facilitate the identification of genes affecting traits which are divergent in these two Iranian sheep breeds.

Cites

No record.

References

No record.

Cite

APA: Copy

MORADI, M.H., NEJATI JAVAREMI, A., MORADI SHAHRBABAK, M., DODDS, K.G., & MCEWAN, J.C.. (2010). WHOLE-GENOME SCAN OF POPULATION DIFFERENTIATION IN ZEL AND LORI-BAKHTIARI SHEEP BREEDS. JOURNAL OF AGRICULTURAL BIOTECHNOLOGY, 2(2), 57-70. SID. https://sid.ir/paper/224358/en

Vancouver: Copy

MORADI M.H., NEJATI JAVAREMI A., MORADI SHAHRBABAK M., DODDS K.G., MCEWAN J.C.. WHOLE-GENOME SCAN OF POPULATION DIFFERENTIATION IN ZEL AND LORI-BAKHTIARI SHEEP BREEDS. JOURNAL OF AGRICULTURAL BIOTECHNOLOGY[Internet]. 2010;2(2):57-70. Available from: https://sid.ir/paper/224358/en

IEEE: Copy

M.H. MORADI, A. NEJATI JAVAREMI, M. MORADI SHAHRBABAK, K.G. DODDS, and J.C. MCEWAN, “WHOLE-GENOME SCAN OF POPULATION DIFFERENTIATION IN ZEL AND LORI-BAKHTIARI SHEEP BREEDS,” JOURNAL OF AGRICULTURAL BIOTECHNOLOGY, vol. 2, no. 2, pp. 57–70, 2010, [Online]. Available: https://sid.ir/paper/224358/en

Related Journal Papers