GENIC VARIANT DETECTION OF CASPIAN HORSE USING HIGH-THROUGHPUT SEQUENCING TECHNOLOGY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AREFNEZHAD B.; KOHRAM H.; MORADI SHAHRE BABAK M.; SHAKERI M.; DONG Y.; ZHANG X.; WANG W.; HOSSEINI SALEKDEH GH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF AGRICULTURAL BIOTECHNOLOGY Year:2015 | Volume:6 | Issue:4 Page(s): 101-116

Download Full-Text

Persian Verion

View:

1,241

Download:

Cites:

Information Journal Paper

Title

GENIC VARIANT DETECTION OF CASPIAN HORSE USING HIGH-THROUGHPUT SEQUENCING TECHNOLOGY

Author(s)

Keywords

HIGH-THROUGHPUT SEQUENCINGQ2

CASPIAN HORSEQ2

GENIC VARIANTSQ2

BIOLOGICAL PATHWAYSQ2

Abstract

Recently, new advanced HIGH-THROUGHPUT SEQUENCING technology as a novel tool has opened the way to study of genomic variants and functional information stored within farm animals. The CASPIAN HORSE is one of the valuable horses ever exist in the world. Hence, propose of this study was to investigate genetic variants of single nucleotide polymorphisms, insertion and deletions and copy number variations within the genome of CASPIAN HORSE and their involved BIOLOGICAL PATHWAYS. Using HIGH-THROUGHPUT SEQUENCING technology, we generated 108 Gb (Average depth of 45.8) of DNA sequence from three CASPIAN HORSE mares resulting in an average of 14.41X coverage and 76.4% covered with reference genome. Using a stringent filtering method, we identified 1666717 single nucleotide polymorphisms, 358020 insertion and deletions, and 3109 copy number variations. Functional clustering analysis of GENIC VARIANTS revealed that most of the genetic variants in the CASPIAN HORSE’s genome were enriched in nervous system, GTP-related signal transduction, cellular morphogenesis, cytoskeleton organization, vascular development and cellular movement. Moreover, we have detected structural variations as like as inversion, intraand inter-chromosomal translocations, large insertion and deletions which could be useful for marker based population genetic investigation.

Cites

No record.

References

No record.

Cite

APA: Copy

AREFNEZHAD, B., KOHRAM, H., MORADI SHAHRE BABAK, M., SHAKERI, M., DONG, Y., ZHANG, X., WANG, W., & HOSSEINI SALEKDEH, GH.. (2015). GENIC VARIANT DETECTION OF CASPIAN HORSE USING HIGH-THROUGHPUT SEQUENCING TECHNOLOGY. JOURNAL OF AGRICULTURAL BIOTECHNOLOGY, 6(4), 101-116. SID. https://sid.ir/paper/224371/en

Vancouver: Copy

AREFNEZHAD B., KOHRAM H., MORADI SHAHRE BABAK M., SHAKERI M., DONG Y., ZHANG X., WANG W., HOSSEINI SALEKDEH GH.. GENIC VARIANT DETECTION OF CASPIAN HORSE USING HIGH-THROUGHPUT SEQUENCING TECHNOLOGY. JOURNAL OF AGRICULTURAL BIOTECHNOLOGY[Internet]. 2015;6(4):101-116. Available from: https://sid.ir/paper/224371/en

IEEE: Copy

B. AREFNEZHAD, H. KOHRAM, M. MORADI SHAHRE BABAK, M. SHAKERI, Y. DONG, X. ZHANG, W. WANG, and GH. HOSSEINI SALEKDEH, “GENIC VARIANT DETECTION OF CASPIAN HORSE USING HIGH-THROUGHPUT SEQUENCING TECHNOLOGY,” JOURNAL OF AGRICULTURAL BIOTECHNOLOGY, vol. 6, no. 4, pp. 101–116, 2015, [Online]. Available: https://sid.ir/paper/224371/en

Related Journal Papers