Investigation of Fabrication and Synthesis of Cappa-Carrageenan/Silk Fibroin Nanofibers Scaffolds for Bone Tissue Engineering

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Roshanfar Fahimeh; MAZIDI ARASH; Noori Alireza; Roshanfar Farideh

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Journal: JOURNAL OF ADVANCED MATERIALS AND TECHNOLOGIES Year:2018 | Volume:7 | Issue:3 Page(s): 1-10

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Title

Investigation of Fabrication and Synthesis of Cappa-Carrageenan/Silk Fibroin Nanofibers Scaffolds for Bone Tissue Engineering

Author(s)

Roshanfar Fahimeh | MAZIDI ARASH | Noori Alireza | Roshanfar Farideh | Issue Writer Certificate

Keywords

biocompositeQ1

Calcium PhosphateQ2

K-CarrageenanQ1

Silk Fibroin NanofiberQ1

Bone Tissue EngineeringQ1

Abstract

Bone defect is one of the important challenges of medical science. Today, the synthesis of a suitable scaffold has been developed. In this paper, new bioactive composite scaffolds based on kappa-carrageenan/fibrobin nanofibers were synthesized and characterized for bone regeneration applications. The fibroin nanofibers were prepared by electrospinning, then the chopped electrospun nanofibers were incorporated to Kappa-carrageenan solution (0. 5% w/v) in different ratios as a reinforcer. Finally, 3D scaffolds were fabricated by Freeze-drying. The results of scanning electron microscopy showed the highly porous structure with the interconnected porous. The porosity percentage and average pore size of the scaffolds were suitable for bone cells implantation and propagation. In addition, Energy Dispersive X ray (EDS) technique has proved Precipitation of Ca-P on the surfaces. The biocompatibility evaluation of fabricated scaffolds was done using MTT indirect assay.

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APA: Copy

Roshanfar, Fahimeh, MAZIDI, ARASH, Noori, Alireza, & Roshanfar, Farideh. (2018). Investigation of Fabrication and Synthesis of Cappa-Carrageenan/Silk Fibroin Nanofibers Scaffolds for Bone Tissue Engineering. JOURNAL OF ADVANCED MATERIALS AND TECHNOLOGIES, 7(3 ), 1-10. SID. https://sid.ir/paper/252433/en

Vancouver: Copy

Roshanfar Fahimeh, MAZIDI ARASH, Noori Alireza, Roshanfar Farideh. Investigation of Fabrication and Synthesis of Cappa-Carrageenan/Silk Fibroin Nanofibers Scaffolds for Bone Tissue Engineering. JOURNAL OF ADVANCED MATERIALS AND TECHNOLOGIES[Internet]. 2018;7(3 ):1-10. Available from: https://sid.ir/paper/252433/en

IEEE: Copy

Fahimeh Roshanfar, ARASH MAZIDI, Alireza Noori, and Farideh Roshanfar, “Investigation of Fabrication and Synthesis of Cappa-Carrageenan/Silk Fibroin Nanofibers Scaffolds for Bone Tissue Engineering,” JOURNAL OF ADVANCED MATERIALS AND TECHNOLOGIES, vol. 7, no. 3 , pp. 1–10, 2018, [Online]. Available: https://sid.ir/paper/252433/en

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