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Title

STUDY OF THE EFFECT OF COMPOUND SYZYGIUM AROMATICUM AND RHEUM OFFICINALE EXTRACT ON SKIN WOUND HEALING IN RAT

Pages

  49-56

Abstract

 In the present study efficacy ofEugenia caryophilla and RHEUM OFFICINALE extract have been investigated on the wound healing. Forty Wistar RATs, weighting 200-250 g, were taken for this study.A full thickness wound in 1 cm length was created on the paravertebral region of each animal. Then animals were divided to experiment (n=20) and control groups (n=20), randomly. Wounds of animals in experiment group were treated with combinedEugenia caryophilla and RHEUM OFFICINALE extracts twice a day for 3 days. On days 3, 7, 10 and 14, after assessment of wound contraction RATe, 5 RATs of each group were euthanized and tissue samples were obtained for histopathologic examination. In this study wound contraction was more evident in experiment group than control group in all days, however there was no significant difference between them (p<0.05). Histopathologic examination showed that inflammation has been reduced significantly on days 3 in experiment group when compared to control group. Other indices of wound healing were better in experiment group in all days, but there were not any significant differences between 2 groups. Results of the present study showed that using ofEugenia caryophilla and RHEUM OFFICINALE extracts gel to SKIN WOUND in RATs, causes significant reduction of inflammation, particularly in first hours after wound creation that resulted in acceleration of wound healing.

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    APA: Copy

    KARIMI, I., & DABILI, A.. (2016). STUDY OF THE EFFECT OF COMPOUND SYZYGIUM AROMATICUM AND RHEUM OFFICINALE EXTRACT ON SKIN WOUND HEALING IN RAT. IRANIAN JOURNAL OF VETERINARY CLINICAL SCIENCES, 9(2), 49-56. SID. https://sid.ir/paper/260074/en

    Vancouver: Copy

    KARIMI I., DABILI A.. STUDY OF THE EFFECT OF COMPOUND SYZYGIUM AROMATICUM AND RHEUM OFFICINALE EXTRACT ON SKIN WOUND HEALING IN RAT. IRANIAN JOURNAL OF VETERINARY CLINICAL SCIENCES[Internet]. 2016;9(2):49-56. Available from: https://sid.ir/paper/260074/en

    IEEE: Copy

    I. KARIMI, and A. DABILI, “STUDY OF THE EFFECT OF COMPOUND SYZYGIUM AROMATICUM AND RHEUM OFFICINALE EXTRACT ON SKIN WOUND HEALING IN RAT,” IRANIAN JOURNAL OF VETERINARY CLINICAL SCIENCES, vol. 9, no. 2, pp. 49–56, 2016, [Online]. Available: https://sid.ir/paper/260074/en

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