Empirical study of Geometrical and Fluidic Parameters on Size of Droplets in Microfluidic Devices with Flow-Focusing Confinement

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Chimerad Mohammad Reza; ASIAEI SASAN; Moghadasi Hesam; GHORBANI BIDKORBEH FATEMEH

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Paper Information

Journal: JOURNAL OF MECHANICAL ENGINEERING Year:2020 | Volume:50 | Issue:3 (92) Page(s): 25-30

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Information Journal Paper

Title

Empirical study of Geometrical and Fluidic Parameters on Size of Droplets in Microfluidic Devices with Flow-Focusing Confinement

Author(s)

Chimerad Mohammad Reza | ASIAEI SASAN | Moghadasi Hesam | GHORBANI BIDKORBEH FATEMEH | Issue Writer Certificate

Keywords

Microfluidic

Empirical Study

Droplets

Geometric Parameters

Fluid Characteristics

Abstract

One of the most important challenges faced by pharmacists is the inability to produce drug carriers with precision and control in a specific number. Therefore, droplet production with the aid of Microfluidic devices as adaptive devices with the wide range of application is used. The purpose of this research is producing Droplets as a structure for drug carrier with the aid of Microfluidic devices with flow-focusing geometry. Also, the effect of geometrical, mechanical and Fluid Characteristics on the diameter of the produced Droplets (Using two types of oily paraffin and hexadecane separately as continuous fluid and water as a discrete fluid) has been evaluated, empirically. As a results, by increasing the angle between the main and secondary channels and increasing the width of the channels, the diameter of the Droplets expanded exponentially and relatively linearly, respectively. However, by decreasing the viscosity ratio to the surface tension of the fluid, the diameter of the produced Droplets decreases relatively linearly. Moreover, in all studies, when the regimen changes, the mutation of the microchip occurs, In addition, the flow rate of continuous phase increases and the diameter of the produced Droplets decreases.

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APA: Copy

Chimerad, Mohammad Reza, ASIAEI, SASAN, Moghadasi, Hesam, & GHORBANI BIDKORBEH, FATEMEH. (2020). Empirical study of Geometrical and Fluidic Parameters on Size of Droplets in Microfluidic Devices with Flow-Focusing Confinement. JOURNAL OF MECHANICAL ENGINEERING, 50(3 (92) ), 25-30. SID. https://sid.ir/paper/269857/en

Vancouver: Copy

Chimerad Mohammad Reza, ASIAEI SASAN, Moghadasi Hesam, GHORBANI BIDKORBEH FATEMEH. Empirical study of Geometrical and Fluidic Parameters on Size of Droplets in Microfluidic Devices with Flow-Focusing Confinement. JOURNAL OF MECHANICAL ENGINEERING[Internet]. 2020;50(3 (92) ):25-30. Available from: https://sid.ir/paper/269857/en

IEEE: Copy

Mohammad Reza Chimerad, SASAN ASIAEI, Hesam Moghadasi, and FATEMEH GHORBANI BIDKORBEH, “Empirical study of Geometrical and Fluidic Parameters on Size of Droplets in Microfluidic Devices with Flow-Focusing Confinement,” JOURNAL OF MECHANICAL ENGINEERING, vol. 50, no. 3 (92) , pp. 25–30, 2020, [Online]. Available: https://sid.ir/paper/269857/en

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