Cold atmospheric plasma as a promising approach for gelatin immobilization on poly(ε ‑ caprolactone) electrospun scaffolds

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Meghdadi Marziyeh; ATYABI SEYED MOHAMMAD; PEZESHKI MODARESS MOHAMAD; IRANI SHIVA; NOORMOHAMMADI ZAHRA; ZANDI MOJGAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: PROGRESS IN BIOMATERIALS Year:2019 | Volume:8 | Issue:2 Page(s): 65-75

Download Full-Text

View:

146

Download:

128

Cites:

Information Journal Paper

Title

Cold atmospheric plasma as a promising approach for gelatin immobilization on poly(ε ‑ caprolactone) electrospun scaffolds

Author(s)

Keywords

Cold atmospheric plasma ·

PCL ·

Nanofibers ·

Grafting ·

Gelatin

Abstract

Poly(Ɛ-caprolactone) (PCL) is a biocompatible polymer with a high potential to be used in tissue engineering especially in tight tissues. In the current study, cold atmospheric plasma (CAP) is used as a promising method for immobilization of Gelatin as a functional biomacromolecule on PCL nanofibrous substrates. The CAP surface modification leads to oxidation of chemical groups existing on the PCL surface without doing any damage to the bulk properties of biomaterials for Gelatin biomacromolecule grafting. The water contact angle (WCA) of the CAP-treated surface and Gelatin-grafted PCL using CAP indicates an effective increment in the hydrophilicity of the PCL surface. Also to achieve the highest levels of Gelatin grafting on the PCL surface, two different grafting methods and Gelatin concentration diversity are utilized in the grafting process. The immobilization of Gelatin biomacromolecules onto the CAP surface-modified PCL nanofibers is investigated using scanning electron microscope (SEM) and Fourier transform infrared spectroscopy (FTIR). The Gelatin-modified PCL substrates revealed uniform nanofibrous morphology with increased average fiber diameter. The results of FTIR spectra, including hydroxyl groups, NH groups, and amide II of Gelatin-grafting peaks, confirm the Gelatin immobilization on the surface of nanofibers. The metabolic activity of cultured mesenchymal stem cells (MSCs) on the surface-modified scaffolds is evaluated using MTT analysis (P ≤ 0. 05). The results of metabolic activity and also SEM and DAPI staining observations indicate proper attachment on the surface and viability for MSCs on the surface-immobilized nanofibrous scaffolds. Therefore, CAP treatment would be an effective method for biomacromolecule immobilization on nanofibers towards the enhancement of cell behavior.

Cites

Bioactivity Determination of Recombinant lysostaphin Immobilized on Glass Surfaces Modified by Cold Atmospheric Plasma on Staphylococcus aureus

References

Cite

APA: Copy

Meghdadi, Marziyeh, ATYABI, SEYED MOHAMMAD, PEZESHKI MODARESS, MOHAMAD, IRANI, SHIVA, NOORMOHAMMADI, ZAHRA, & ZANDI, MOJGAN. (2019). Cold atmospheric plasma as a promising approach for gelatin immobilization on poly(ε ‑ caprolactone) electrospun scaffolds. PROGRESS IN BIOMATERIALS, 8(2), 65-75. SID. https://sid.ir/paper/336552/en

Vancouver: Copy

Meghdadi Marziyeh, ATYABI SEYED MOHAMMAD, PEZESHKI MODARESS MOHAMAD, IRANI SHIVA, NOORMOHAMMADI ZAHRA, ZANDI MOJGAN. Cold atmospheric plasma as a promising approach for gelatin immobilization on poly(ε ‑ caprolactone) electrospun scaffolds. PROGRESS IN BIOMATERIALS[Internet]. 2019;8(2):65-75. Available from: https://sid.ir/paper/336552/en

IEEE: Copy

Marziyeh Meghdadi, SEYED MOHAMMAD ATYABI, MOHAMAD PEZESHKI MODARESS, SHIVA IRANI, ZAHRA NOORMOHAMMADI, and MOJGAN ZANDI, “Cold atmospheric plasma as a promising approach for gelatin immobilization on poly(ε ‑ caprolactone) electrospun scaffolds,” PROGRESS IN BIOMATERIALS, vol. 8, no. 2, pp. 65–75, 2019, [Online]. Available: https://sid.ir/paper/336552/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops