EXPERIMENTAL INTOXICATION BY ECHIUM ITALICUM IN NATIVE CALVES

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MAHAM M.; HOBENAGHI R.; HADIAN M.

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Paper Information

Journal: Journal of Veterinary Research Year:2003 | Volume:58 | Issue:4 Page(s): 363-367

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Information Journal Paper

Title

EXPERIMENTAL INTOXICATION BY ECHIUM ITALICUM IN NATIVE CALVES

Author(s)

MAHAM M. | HOBENAGHI R. | HADIAN M. | Issue Writer Certificate

Keywords

ECHIUMQ4

PLANT POISONINGQ4

CALFQ3

PYRROLIZIDINE ALKALOIDSQ4

Abstract

Objective: To identify the clinical signs, clinical pathology and pathological findings in experimental ECHIUM italicum poisoning in native calves. Design: Interventional study. Animals: Ten native calves aged 5 to 7 months in two groups (experiment and control). Procedure: The fresh E. italicum was fed as the sole diet to experimental calves during 8 weeks. Calcium, phosphorus, sodium, creatinine, BUN, AST and GGT were determined in serum of calves at weekly intervals during the period of experiment. Histopathological examinations were performed on tissue samples. Statistical analysis: One way ANOVA. Results: This experimental study revealed a significant increase in serum calcium, GGT and AST (P<0.05). During the trial, one of the 5 calves on the ECHIUM diet died in day 49 without showing any symptoms before. The calves of experimental group showed similar histological changes in liver, such as centrilobular necrosis, portal triad fibrosis and bile duct proliferation with polymorph neutrophil infiltration. In the asymptomatic CALF, the kidneys showed acute tubular necrosis. Clinical implications: It is concluded that E. italicum is not a suitable fodder for calves and can be toxic due to its PYRROLIZIDINE ALKALOIDS.

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APA: Copy

MAHAM, M., HOBENAGHI, R., & HADIAN, M.. (2003). EXPERIMENTAL INTOXICATION BY ECHIUM ITALICUM IN NATIVE CALVES. JOURNAL OF VETERINARY RESEARCH, 58(4), 363-367. SID. https://sid.ir/paper/34524/en

Vancouver: Copy

MAHAM M., HOBENAGHI R., HADIAN M.. EXPERIMENTAL INTOXICATION BY ECHIUM ITALICUM IN NATIVE CALVES. JOURNAL OF VETERINARY RESEARCH[Internet]. 2003;58(4):363-367. Available from: https://sid.ir/paper/34524/en

IEEE: Copy

M. MAHAM, R. HOBENAGHI, and M. HADIAN, “EXPERIMENTAL INTOXICATION BY ECHIUM ITALICUM IN NATIVE CALVES,” JOURNAL OF VETERINARY RESEARCH, vol. 58, no. 4, pp. 363–367, 2003, [Online]. Available: https://sid.ir/paper/34524/en

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