EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICAL AND BIOCHEMICAL FACTORS IN DONKEYS (EQQUSASINUS)

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BADIEI KHALIL; NOUROUZIASL A.; POURJAFAR MEHRDAD; NIKAHVAL B.; ABNA ROUDHELEH F.

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Journal: Journal of Veterinary Research Year:2008 | Volume:63 | Issue:4 Page(s): 215-220

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Title

EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICAL AND BIOCHEMICAL FACTORS IN DONKEYS (EQQUSASINUS)

Author(s)

Keywords

IVERMECTINQ3

BLOODQ2

HAEMATOLOGYQ2

BIOCHEMISTRYQ2

DONKEYQ3

Abstract

Five healthy adult male Iranian DONKEYs (Equus asinus) were selected and IVERMECTIN (0.2, 0.6 and 0.9 mg/kg, orally at different times) for 14 days was administered. Before dosing, control BLOOD samples were taken on day 0.Blood samples were taken on days 1,2,3,7 and 14 following IVERMECTIN administration at different doses. The results showed that the activity of serum AST and LD R increased on days 7 and 14 following IVERMECTIN (0.2, 0.6 and 0.9 mg/kg, orally) administration (p<0.05). ALP activity and BUN concentration increased significantly on day 14 following IVERMECTIN (0.2, 0.6 and 0.9 mg/kg, orally) administration (p<0.05). Changes of ablumin, creatinin, glucose, total protein, Phosphorous and calcium concentrations and hemoglobin, PCV, MCR, MCHC, MCV and percentages of neutrophils, eosinophils, monocytes, lymphocytes and platelet numbers were not significant (p>0.05). As it was shown in short term, no abnormal clinical and laboratory findings were detected following different oral doses of IVERMECTIN and it seems that the drug can be safely administered to this species.

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APA: Copy

BADIEI, KHALIL, NOUROUZIASL, A., POURJAFAR, MEHRDAD, NIKAHVAL, B., & ABNA ROUDHELEH, F.. (2008). EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICAL AND BIOCHEMICAL FACTORS IN DONKEYS (EQQUSASINUS). JOURNAL OF VETERINARY RESEARCH, 63(4), 215-220. SID. https://sid.ir/paper/35229/en

Vancouver: Copy

BADIEI KHALIL, NOUROUZIASL A., POURJAFAR MEHRDAD, NIKAHVAL B., ABNA ROUDHELEH F.. EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICAL AND BIOCHEMICAL FACTORS IN DONKEYS (EQQUSASINUS). JOURNAL OF VETERINARY RESEARCH[Internet]. 2008;63(4):215-220. Available from: https://sid.ir/paper/35229/en

IEEE: Copy

KHALIL BADIEI, A. NOUROUZIASL, MEHRDAD POURJAFAR, B. NIKAHVAL, and F. ABNA ROUDHELEH, “EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICAL AND BIOCHEMICAL FACTORS IN DONKEYS (EQQUSASINUS),” JOURNAL OF VETERINARY RESEARCH, vol. 63, no. 4, pp. 215–220, 2008, [Online]. Available: https://sid.ir/paper/35229/en

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