Impact of Application of Natural Toxin Binder on Performance, Humoral Immune Response, Cecal Microbial Population and Chages in Small Intestine Mophology of Broilers Fed with Diet Contaminated with Aflatoxin B1

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MANAFI M.

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Journal: Journal of Veterinary Research Year:2018 | Volume:73 | Issue:3 Page(s): 273-282

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Title

Impact of Application of Natural Toxin Binder on Performance, Humoral Immune Response, Cecal Microbial Population and Chages in Small Intestine Mophology of Broilers Fed with Diet Contaminated with Aflatoxin B1

Author(s)

MANAFI M. | Issue Writer Certificate

Keywords

BroilersQ2

PerformanceQ2

Intestinal morphologyQ1

Natural toxin binderQ1

AflatoxicosisQ1

Abstract

BACKGROUND: Aflatoxin contamination in animal and poultry and its carry over to human beings is important in causing different diseases like Hepatitis and Liver Cirrhosis and finding methods to lessen toxin adsorption in animal and poultry tissues has a direct impact on health of animal products. OBJECTIVES: Evaluating the impact of Natural toxin binder in Broilers contaminated with aflatoxin B1 on Performance, immunity and morpholgy of intestine. METHODS: 400 day-old broiler chicks under 4 treatments, 5 replicates and 20 chicks per replicate in completely randomized design manner were studied for 42 days. Experimental treatments were: 1-negative control (basal diet with out aflatoxin contamination); 2-positive control (basal diet + 0. 6 mg/kg aflatoxin B1; 3-basal diet along with 1g/kg Natural toxin binder and 4-basal diet + 1g/kg Natural toxin binder. RESULTS: Presence of aflatoxin in diet reduced all Performance indexes significantly (p<0. 05) on day 42 and using Natural toxin binder could reduce the negative effects of aflatoxin and improved body weight, feed consumption and feed conversion ratio, when compared with treatment fed with aflatoxin. Significant (p<0. 05) enhancement in immune titer responses against Newcastle and Avian Influenza were noticed in group fed Natural toxin binder, compared with control aflatoxin contaminated treatment. The significant (p<0. 05) reduction in E. coli and coliforms were seen in tratment 4, when compared with treatment 2. The crypt to depth ration was increased and the number of goblet cells decreased significantly (p<0. 05) in positive control teratment which received Natural toxin binder, compared with control group. CONCLUSIONS: Results obtained from current study emphasized on the possible replacement of Natural toxin binders rather than chemical-commercial toxin binders.

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APA: Copy

MANAFI, M.. (2018). Impact of Application of Natural Toxin Binder on Performance, Humoral Immune Response, Cecal Microbial Population and Chages in Small Intestine Mophology of Broilers Fed with Diet Contaminated with Aflatoxin B1. JOURNAL OF VETERINARY RESEARCH, 73(3 ), 273-282. SID. https://sid.ir/paper/35573/en

Vancouver: Copy

MANAFI M.. Impact of Application of Natural Toxin Binder on Performance, Humoral Immune Response, Cecal Microbial Population and Chages in Small Intestine Mophology of Broilers Fed with Diet Contaminated with Aflatoxin B1. JOURNAL OF VETERINARY RESEARCH[Internet]. 2018;73(3 ):273-282. Available from: https://sid.ir/paper/35573/en

IEEE: Copy

M. MANAFI, “Impact of Application of Natural Toxin Binder on Performance, Humoral Immune Response, Cecal Microbial Population and Chages in Small Intestine Mophology of Broilers Fed with Diet Contaminated with Aflatoxin B1,” JOURNAL OF VETERINARY RESEARCH, vol. 73, no. 3 , pp. 273–282, 2018, [Online]. Available: https://sid.ir/paper/35573/en

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