Effect of oral administration of the bovine injectable formulation of enrofloxacin (Enrofan 5™ ) on hematological parameters in horse

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ALIDADI N.; ATYABI N.; RASSOULI A.; GHADAMI S.; AKBAREIN H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL Year:2018 | Volume:14 | Issue:3 Page(s): 50-56

Download Full-Text

Persian Verion

View:

803

Download:

Cites:

Information Journal Paper

Title

Effect of oral administration of the bovine injectable formulation of enrofloxacin (Enrofan 5™ ) on hematological parameters in horse

Author(s)

Keywords

EnrofloxacinQ2

Oral administrationQ1

HematologyQ2

HorseQ3

Abstract

Enrofloxacin is a useful antimicrobial drug for treatment of infectious diseases in the Horse. The present study carried out due to the limitation of the approved route of administration of the drug (intravenous) and lack of data on its potential effects on hematological parameters in this animal species. Nine healthy mixed– bred (6 female and 3 male) Horses, aged between 1-15 years, were randomly divided into three experimental groups (each 3 animals): Control group (with no drug dosing), Enrofloxacin moderate-dose and Enrofloxacin high-dose groups (using the bovine 5% Enrofloxacin solution at 5 or 15 mg/kg body weight, respectively, every 12 hours, for three weeks). In addition to physical examination of all Horses, blood samples were collected at five-time points during the study period including before (day 0), during (days 7, 14 and 21) and 4 weeks after completion of drug administration (day 49). Routine hematological tests were done on samples and data of three groups and trend of alterations of hematologic and biochemical parameters were analyzed. There were no significant changes in hematological parameters including hematocrit (PCV), hemoglobin (Hb), red blood cell (RBC) counts, white blood cell (WBC) and differential counts, platelets, as well as total plasma protein and fibrinogen levels among three groups during 5 sampling time points. The results suggest there were no significant hematological changes due to Enrofloxacin at given dosing rates but more studies are needed in this regard.

Cites

No record.

References

No record.

Cite

APA: Copy

ALIDADI, N., ATYABI, N., RASSOULI, A., GHADAMI, S., & AKBAREIN, H.. (2018). Effect of oral administration of the bovine injectable formulation of enrofloxacin (Enrofan 5™ ) on hematological parameters in horse. SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, 14(3 ), 50-56. SID. https://sid.ir/paper/357374/en

Vancouver: Copy

ALIDADI N., ATYABI N., RASSOULI A., GHADAMI S., AKBAREIN H.. Effect of oral administration of the bovine injectable formulation of enrofloxacin (Enrofan 5™ ) on hematological parameters in horse. SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL[Internet]. 2018;14(3 ):50-56. Available from: https://sid.ir/paper/357374/en

IEEE: Copy

N. ALIDADI, N. ATYABI, A. RASSOULI, S. GHADAMI, and H. AKBAREIN, “Effect of oral administration of the bovine injectable formulation of enrofloxacin (Enrofan 5™ ) on hematological parameters in horse,” SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, vol. 14, no. 3 , pp. 50–56, 2018, [Online]. Available: https://sid.ir/paper/357374/en

Related Journal Papers