A molecular study on genetic structure of interleukin 2 in Khorasan native chicken

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Tohidi Reza; Dousti Mohammad; Nasiri Mohammadreza; Javanmard Arash

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Animal Science Journal Year:2018 | Volume:31 | Issue:119 Page(s): 209-218

Download Full-Text

Persian Verion

View:

372

Download:

Cites:

Information Journal Paper

Title

A molecular study on genetic structure of interleukin 2 in Khorasan native chicken

Author(s)

Tohidi Reza | Dousti Mohammad | Nasiri Mohammadreza | Javanmard Arash | Issue Writer Certificate

Keywords

geneQ1

interleukin 2Q1

SequencingQ1

Khorasan native chickenQ1

Abstract

Control of diseases is one of the concerns in poultry industry worldwide. Despite the use of proper vaccines, antibiotics and sanitation in poultry farms, still disease outbreaks make irreparable economical loss. Another effective way of increasing the resistance of poultry to diseases is the genetic improvement of the immune system, which can reduce the current cost of taking vaccine and medicine. Considering the importance of IL-2 in the immune system, the present study was conducted to investigate the structure of IL-2 gene in Khorasan native chickens. To conduct this research, 20 DNA samples from Khorasan native chickens were used to amplify and sequence of 875-base pairs from the IL-2 gene. Comparison of the sequences obtained from the Khorasan native chickens with the sequence deposited in the NCBI showed mutations in the IL-2 gene, so that these mutations in the exon 1 region altered the amino acids. Exon mutations at 733, 738, 744 and 794 base pairs made to replace adenine bases instead of cytosine, thymine instead of adenine, adenine instead of cytosine, and thymine instead of cytosine. Identifying these mutations can allow them to be used as a genetic marker. To confirm this, we need to investigate the frequency of mutations and also examine their effect on IL-2 performance through proteomics experiments.

Cites

No record.

References

No record.

Cite

APA: Copy

Tohidi, Reza, Dousti, Mohammad, Nasiri, Mohammadreza, & Javanmard, Arash. (2018). A molecular study on genetic structure of interleukin 2 in Khorasan native chicken. ANIMAL SCIENCES JOURNAL (PAJOUHESH & SAZANDEGI), 31(119 ), 209-218. SID. https://sid.ir/paper/370452/en

Vancouver: Copy

Tohidi Reza, Dousti Mohammad, Nasiri Mohammadreza, Javanmard Arash. A molecular study on genetic structure of interleukin 2 in Khorasan native chicken. ANIMAL SCIENCES JOURNAL (PAJOUHESH & SAZANDEGI)[Internet]. 2018;31(119 ):209-218. Available from: https://sid.ir/paper/370452/en

IEEE: Copy

Reza Tohidi, Mohammad Dousti, Mohammadreza Nasiri, and Arash Javanmard, “A molecular study on genetic structure of interleukin 2 in Khorasan native chicken,” ANIMAL SCIENCES JOURNAL (PAJOUHESH & SAZANDEGI), vol. 31, no. 119 , pp. 209–218, 2018, [Online]. Available: https://sid.ir/paper/370452/en

Related Journal Papers