The effects of oral and bath treatment with metronidazole and levamisole on some of the serum enzymes and proteins in common carp (Cyprinus carpio)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Barakitabar S.; PEYGHAN R.; RAZI JALALI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL Year:2019 | Volume:15 | Issue:1 Page(s): 5-14

Download Full-Text

Persian Verion

View:

1,050

Download:

Cites:

Information Journal Paper

Title

The effects of oral and bath treatment with metronidazole and levamisole on some of the serum enzymes and proteins in common carp (Cyprinus carpio)

Author(s)

Barakitabar S. | PEYGHAN R. | RAZI JALALI M. | Issue Writer Certificate

Keywords

Common carpQ2

MetronidazoleQ2

LevamisoleQ2

EnzymeQ2

ElectrophoresisQ3

Abstract

Metronidazole and Levamisole have several clinical and biochemical side effects such as changes in the activity of serum Enzymes and proteins and other profiles. There are some reports of Metronidazole and Levamisole effect on blood serum proteins in animals, but there is no report of these drugs on criteria in Common carp. In this study, 150 Common carp (75± 15 gr) were divided randomly into five categories. One group served as the control (no drug) and four treatment groups: Metronidazole bath (5mg/l/24hr in 2 days interval), Oral Metronidazole (5mg/kg/10 days), Levamisole bath (5mg/l/24hr in 2 days interval) and Oral Levamisole (5mg/kg/10days) were considered. After 10 days, on days 1, 7 and 14 after completion of treatment, blood samples were collected from fish and serum total protein in combination with Electrophoresis and the activity of serum Enzymes (AST, ALT and ALP) were performed. The results showed that there was no significant difference in plasma total protein in the studied groups compared to the control group. Serum Enzymes activity in the control group was not significantly different between the two groups of Levamisole bath and oral Levamisole except for alkaline phosphatase. Aspartate aminotransferase Enzyme activity in the oral Metronidazole group was significantly higher than the control group. The mean values of albumin, alpha-1 globulin, alpha-2 globulins, beta-globulins and gamma globulins in the control group did not significantly differ with other groups. Based on the findings of this study, it can be concluded that Levamisole and Metronidazole drugs in the recommended doses in these treatments have altered some of the serum indices but did not significantly increase the number of studied factors. It does not have a significant effect on blood protein factors and it is advisable to recommend it as an antiparasitic treatment in Common carp, although supplementary research seems necessary in this regard.

Cites

No record.

References

No record.

Cite

APA: Copy

Barakitabar, S., PEYGHAN, R., & RAZI JALALI, M.. (2019). The effects of oral and bath treatment with metronidazole and levamisole on some of the serum enzymes and proteins in common carp (Cyprinus carpio). SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, 15(1 ), 5-14. SID. https://sid.ir/paper/379902/en

Vancouver: Copy

Barakitabar S., PEYGHAN R., RAZI JALALI M.. The effects of oral and bath treatment with metronidazole and levamisole on some of the serum enzymes and proteins in common carp (Cyprinus carpio). SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL[Internet]. 2019;15(1 ):5-14. Available from: https://sid.ir/paper/379902/en

IEEE: Copy

S. Barakitabar, R. PEYGHAN, and M. RAZI JALALI, “The effects of oral and bath treatment with metronidazole and levamisole on some of the serum enzymes and proteins in common carp (Cyprinus carpio),” SCIENTIFIC-RESEARCH IRANIAN VETERINARY JOURNAL, vol. 15, no. 1 , pp. 5–14, 2019, [Online]. Available: https://sid.ir/paper/379902/en

Related Journal Papers