Investigation of the effect of fungal and copper nanocomplexes on bacteria causing nosocomial infections

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Kadoughani Sani Samira; Jamshidian Mojaver Majid; Farzin Hamid Reza; Amiri Mohadeseh

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Journal: NEW FINDINGS IN VETERINARY MICROBIOLOGY Year:2020 | Volume:3 | Issue:1 Page(s): 39-46

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Title

Investigation of the effect of fungal and copper nanocomplexes on bacteria causing nosocomial infections

Author(s)

Kadoughani Sani Samira | Jamshidian Mojaver Majid | Farzin Hamid Reza | Amiri Mohadeseh | Issue Writer Certificate

Keywords

Copper nanoparticles

Ganoderma lucidum

Nosocomial infection

Standard bacterial strains

Abstract

Nosocomial infection is considered as one of the major and most basic medical problems in all hospitals and affects an average of 5 to 10% of hospitalized patients. Exacerbating factors of Nosocomial infections include frequent use of tools as well as repeated contacts with medical staff. In this study, the antibacterial effects of Copper nanoparticles using aqueous extract of Ganoderma lucidum on standard strains of Staphylococcus aureus, Acinetobacter baumannii and Streptococcus pyogenes and Pseudomonas aeruginosa Which are the cause of nos-ocomial infections were investigated. electron microscopy was used to measure the dimensions and shape of cop-per nanoparticles. Infrared spectroscopy was also performed to investigate possible organic compounds that could be involved in the synthesis of nanoparticles. Also, to observe the effectiveness of this nanocomplex, MTT test was performed on two vero cell lines and L 929 fibroblast cell line. The results of scanning electron microscopy in this study showed that the sample of the extract in morphology is completely uniform. Copper nanoparticles are spherical and in the range of 20-30 nm. Also, in the study of mtt test, ANOVA test showed that the value of Sig is zero, which indicates a significant difference between different concentrations and positive and negative control samples. According to the results of this study, fungal and copper nanocomplexes had a relatively strong antibacterial effect against bacteria that cause Nosocomial infections. The non-toxicity proposal of copper nano-particles should be investigated in laboratory spaces in order to use the antibacterial properties of these nanopar-ticles in human applications.

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APA: Copy

Kadoughani Sani, Samira, Jamshidian Mojaver, Majid, Farzin, Hamid Reza, & Amiri, Mohadeseh. (2020). Investigation of the effect of fungal and copper nanocomplexes on bacteria causing nosocomial infections. NEW FINDINGS IN VETERINARY MICROBIOLOGY, 3(1 ), 39-46. SID. https://sid.ir/paper/391120/en

Vancouver: Copy

Kadoughani Sani Samira, Jamshidian Mojaver Majid, Farzin Hamid Reza, Amiri Mohadeseh. Investigation of the effect of fungal and copper nanocomplexes on bacteria causing nosocomial infections. NEW FINDINGS IN VETERINARY MICROBIOLOGY[Internet]. 2020;3(1 ):39-46. Available from: https://sid.ir/paper/391120/en

IEEE: Copy

Samira Kadoughani Sani, Majid Jamshidian Mojaver, Hamid Reza Farzin, and Mohadeseh Amiri, “Investigation of the effect of fungal and copper nanocomplexes on bacteria causing nosocomial infections,” NEW FINDINGS IN VETERINARY MICROBIOLOGY, vol. 3, no. 1 , pp. 39–46, 2020, [Online]. Available: https://sid.ir/paper/391120/en

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