Genotyping of Human Papillomavirus in Cervical Liquid-Based Cytology Specimens

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REZAEI S.; Saadatniya G.; SALEHIAN P.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE) Year:2017 | Volume:2 | Issue:3 Page(s): 165-169

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Information Journal Paper

Title

Genotyping of Human Papillomavirus in Cervical Liquid-Based Cytology Specimens

Author(s)

REZAEI S. | Saadatniya G. | SALEHIAN P. | Issue Writer Certificate

Keywords

Genotyping

Human Papillomavirus

PCR

Hybridization

Abstract

Aims Human Papillomavirus (HPV) is the main cause of cervical cancer and the second cause of cancer mortality among women. Molecular epidemiologic evidence clearly demonstrated that certain types of HPV play a major role in the development of cervical cancer. The objective of this study was to genotype the Human Papillomavirus in cervical liquid-based cytology specimens. Materials & Methods This descriptive cross-sectional study was conducted on 42 liquidbased cytology specimens from women (25-50 years old) referred to the laboratory of Sarem women’ s hospital during one year from 2013 to 2014. Those HPV infections were confirmed by pathological and molecular methods. Polymerase chain reaction (PCR) and Hybridization methods were used to determine the genotypes. Findings Out of the 42 tested samples, 27 cases (64%) belonged to HPV high-risk group that included the types of 16, 18, 31, 33, 56, 58 and 66. Among those 27 samples, 14 (52%) had a combination of infections and 70. 4% of the samples showed infection with types 16 and 18. Conclusion Various types of HPV can be detected in liquid-based cytology specimens and the most common type is HPV16. Simultaneous infections with multiple types of HPV are common in liquid-based cytology specimens of positive women.

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APA: Copy

REZAEI, S., Saadatniya, G., & SALEHIAN, P.. (2017). Genotyping of Human Papillomavirus in Cervical Liquid-Based Cytology Specimens. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), 2(3 ), 165-169. SID. https://sid.ir/paper/401518/en

Vancouver: Copy

REZAEI S., Saadatniya G., SALEHIAN P.. Genotyping of Human Papillomavirus in Cervical Liquid-Based Cytology Specimens. SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2017;2(3 ):165-169. Available from: https://sid.ir/paper/401518/en

IEEE: Copy

S. REZAEI, G. Saadatniya, and P. SALEHIAN, “Genotyping of Human Papillomavirus in Cervical Liquid-Based Cytology Specimens,” SAREM JOURNAL OF MEDICAL RESEARCH (SAREM JOURNAL OF REPRODUCTIVE MEDICINE), vol. 2, no. 3 , pp. 165–169, 2017, [Online]. Available: https://sid.ir/paper/401518/en

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