A NOVEL SYNTHESIS AND CHARACTERIZATION OF POLY[4-IMINO(N-4-ETHYLBENZOATE)BENZENE P-STYRENESULPHONATE] AND THE INVESTIGATION ON POLYMER ABILITY FOR DRUG RELEASE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHAZAEI A.; ZOLFIGOL M.A.; ABEDIAN N.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Polymer Journal Year:2001 | Volume:10 | Issue:1 Page(s): 59-67

Download Full-Text

View:

533

Download:

333

Cites:

Information Journal Paper

Title

A NOVEL SYNTHESIS AND CHARACTERIZATION OF POLY[4-IMINO(N-4-ETHYLBENZOATE)BENZENE P-STYRENESULPHONATE] AND THE INVESTIGATION ON POLYMER ABILITY FOR DRUG RELEASE

Author(s)

KHAZAEI A. | ZOLFIGOL M.A. | ABEDIAN N. | Issue Writer Certificate

Keywords

CONTROLLED DRUG RELEASE

SYNTHESIS

POLYMERIC PRODRUG

BENZOCAINE

Abstract

The present paper describes the release of BENZOCAINE from polymer carrier. The chemically controlled release method has been applied in which the BENZOCAINE (drug) with active group (NH2) links up with the spacer group p-hydroxybenzaldehyde) by imine bond formation. The resulting schiff base reacts with the monomer p-styrenesulphonyl chloride. The obtained monomer is polymerized by AIBN as an initiator at the temperature range 60-70 °C. The obtained polymer was identified by IR and NMR spectroscopies. Gel permeation chromatography (GPC) was used for determination of average molecular weight of drug pendant polymer. The hydrolysis of drug polymer conjugates was carried out in cellophane membrane dialysis bag containing aqueous buffer solution (pH 1.2) at 37 °C. Detection of hydrolysis solution by UV spectroscopy showed that the drug can be released by hydrolysis of imine bond between the drug and spacer group.

Cites

No record.

References

No record.

Cite

APA: Copy

KHAZAEI, A., ZOLFIGOL, M.A., & ABEDIAN, N.. (2001). A NOVEL SYNTHESIS AND CHARACTERIZATION OF POLY[4-IMINO(N-4-ETHYLBENZOATE)BENZENE P-STYRENESULPHONATE] AND THE INVESTIGATION ON POLYMER ABILITY FOR DRUG RELEASE . IRANIAN POLYMER JOURNAL (ENGLISH), 10(1), 59-67. SID. https://sid.ir/paper/527904/en

Vancouver: Copy

KHAZAEI A., ZOLFIGOL M.A., ABEDIAN N.. A NOVEL SYNTHESIS AND CHARACTERIZATION OF POLY[4-IMINO(N-4-ETHYLBENZOATE)BENZENE P-STYRENESULPHONATE] AND THE INVESTIGATION ON POLYMER ABILITY FOR DRUG RELEASE . IRANIAN POLYMER JOURNAL (ENGLISH)[Internet]. 2001;10(1):59-67. Available from: https://sid.ir/paper/527904/en

IEEE: Copy

A. KHAZAEI, M.A. ZOLFIGOL, and N. ABEDIAN, “A NOVEL SYNTHESIS AND CHARACTERIZATION OF POLY[4-IMINO(N-4-ETHYLBENZOATE)BENZENE P-STYRENESULPHONATE] AND THE INVESTIGATION ON POLYMER ABILITY FOR DRUG RELEASE ,” IRANIAN POLYMER JOURNAL (ENGLISH), vol. 10, no. 1, pp. 59–67, 2001, [Online]. Available: https://sid.ir/paper/527904/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops