مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

418
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

341
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

SYNTHESIS AND CHARACTERIZATION OF BIODEGRADABLE IN SITU FORMING HYDROGELS VIA DIRECT OLYCONDENSATION OF POLY(ETHYLENE GLYCOL) AND FUMARIC ACID

Pages

  125-133

Abstract

 Currently, IN SITU FORMING polymeric gels and networks have attracted much attention due to their potential applications as injectable devices in drug delivery and tissue engineering. To this end, biodegradable HYDROGELS were developed based on poly (ethylene glycol)-co-fumaric acid macromers. These macromers were synthesized through DIRECT POLYCONDENSATION of poly (ethylene glycol) of different molecular weights and fumaric acid using dicyclohexylcarbodiimide (DCC) as an esterification promoting agent. They were fully characterized by spectroscopic methods (i.e., Fourier transform infrared and proton nuclear magnetic resonance spectroscopies) and gel permeation chromatography and thermal analysis (i.e., differential scanning calorimetry) techniques. Thermal characterization showed that the produced macromers have lower crystallinity than the original precursors. The molecular weight and the degree of oligomerization of the macromers were also substantially affected by the molecular weights of the initial PEGs. The macromers were cross-linked by redox mechanism in the presence of water soluble initiation system consisting of ammonium persulphate and N,N,N¢,N¢-tetramethylethylenediamine. The swelling properties of the cross-linked gels were also examined which showed a significant dependency to the initial molecular weight of PEGs. Our results have suggested that these biodegradable HYDROGELS are potentially applicable in drug delivery and tissue engineering applications.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    HASHEMI DOULABI, A.S., SHARIFI, SHAHRIAR, IMANI, MOHAMMAD, & MIRZADEH, HAMID. (2008). SYNTHESIS AND CHARACTERIZATION OF BIODEGRADABLE IN SITU FORMING HYDROGELS VIA DIRECT OLYCONDENSATION OF POLY(ETHYLENE GLYCOL) AND FUMARIC ACID . IRANIAN POLYMER JOURNAL (ENGLISH), 17(2), 125-133. SID. https://sid.ir/paper/543208/en

    Vancouver: Copy

    HASHEMI DOULABI A.S., SHARIFI SHAHRIAR, IMANI MOHAMMAD, MIRZADEH HAMID. SYNTHESIS AND CHARACTERIZATION OF BIODEGRADABLE IN SITU FORMING HYDROGELS VIA DIRECT OLYCONDENSATION OF POLY(ETHYLENE GLYCOL) AND FUMARIC ACID . IRANIAN POLYMER JOURNAL (ENGLISH)[Internet]. 2008;17(2):125-133. Available from: https://sid.ir/paper/543208/en

    IEEE: Copy

    A.S. HASHEMI DOULABI, SHAHRIAR SHARIFI, MOHAMMAD IMANI, and HAMID MIRZADEH, “SYNTHESIS AND CHARACTERIZATION OF BIODEGRADABLE IN SITU FORMING HYDROGELS VIA DIRECT OLYCONDENSATION OF POLY(ETHYLENE GLYCOL) AND FUMARIC ACID ,” IRANIAN POLYMER JOURNAL (ENGLISH), vol. 17, no. 2, pp. 125–133, 2008, [Online]. Available: https://sid.ir/paper/543208/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button