THE ROLE OF 5-HT2A AND 5-HT2C RECEPTORS ON HARMALINE-INDUCED EATING BEHAVIOR IN 24-H FOOD-DEPRIVED BROILER COCKERELS

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ZENDEHDEL M.; MOKHTARPOURIANI K.; BABAPOUR V.; POUR RAHIMI M.; HAMIDI F.

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Paper Information

Journal: IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR) Year:2013 | Volume:14 | Issue:2 (43) Page(s): 94-99

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Title

THE ROLE OF 5-HT2A AND 5-HT2C RECEPTORS ON HARMALINE-INDUCED EATING BEHAVIOR IN 24-H FOOD-DEPRIVED BROILER COCKERELS

Author(s)

Keywords

HARMALINE

5-HT

EATING RESPONSE

CHICKEN

Abstract

This study was designed to examine the effects of intracerebroventricular (ICV) injection of ketanserin (5-HT2a receptor antagonist) and SB242084 (5-HT2c receptor antagonist) on HARMALINE induced feeding and drinking response in 24-h food-deprived (FD24) broiler cockerels. At first, guide cannula was surgically implanted in the right lateral ventricle of CHICKENs. In experiment 1, birds were injected intracerebroventriculary with 0, 25, 50 and 100 mg of HARMALINE. In experiment 2, CHICKENs received 10 mg ketanserin prior to the injection of HARMALINE. In experiment 3, birds were administered with HARMALINE after 3 mg SB242084 and the cumulative food and water intake was determined at 3 h post injection. The results of this study showed that HARMALINE decreases food consumption and increases water intake in FD24 broiler cockerels (P£0.05). The effect of HARMALINE on food and water intake was significantly attenuated with ketanserin and SB242084 pretreatment (P£0.05). These results suggest that there is an interaction between HARMALINE and 5-HT (via 5-HT2a and 5-HT2c receptors) on EATING RESPONSE in CHICKEN.

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APA: Copy

ZENDEHDEL, M., MOKHTARPOURIANI, K., BABAPOUR, V., POUR RAHIMI, M., & HAMIDI, F.. (2013). THE ROLE OF 5-HT_2A AND 5-HT_2C RECEPTORS ON HARMALINE-INDUCED EATING BEHAVIOR IN 24-H FOOD-DEPRIVED BROILER COCKERELS. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), 14(2 (43)), 94-99. SID. https://sid.ir/paper/614734/en

Vancouver: Copy

ZENDEHDEL M., MOKHTARPOURIANI K., BABAPOUR V., POUR RAHIMI M., HAMIDI F.. THE ROLE OF 5-HT_2A AND 5-HT_2C RECEPTORS ON HARMALINE-INDUCED EATING BEHAVIOR IN 24-H FOOD-DEPRIVED BROILER COCKERELS. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR)[Internet]. 2013;14(2 (43)):94-99. Available from: https://sid.ir/paper/614734/en

IEEE: Copy

M. ZENDEHDEL, K. MOKHTARPOURIANI, V. BABAPOUR, M. POUR RAHIMI, and F. HAMIDI, “THE ROLE OF 5-HT_2A AND 5-HT_2C RECEPTORS ON HARMALINE-INDUCED EATING BEHAVIOR IN 24-H FOOD-DEPRIVED BROILER COCKERELS,” IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), vol. 14, no. 2 (43), pp. 94–99, 2013, [Online]. Available: https://sid.ir/paper/614734/en

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