THE RELATIONSHIP BETWEEN SERUM COPPER LEVEL WITH COGNITIVE DISORDERS IN ELDERLY

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KHEIRKHAH F.; HOSSEINI S.R.; AZADFORUZ S.; PARSIAN H.; REZAEE H.; MOAUDI S.; BIJANI A.

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Journal Paper

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Journal: AMIRKABIR Year:2016 | Volume:18 | Issue:10 Page(s): 26-31

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Title

THE RELATIONSHIP BETWEEN SERUM COPPER LEVEL WITH COGNITIVE DISORDERS IN ELDERLY

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Keywords

COGNITIVE DISORDERS

ELDERLY

SERUM LEVEL OF COPPER

Abstract

BACKGROUND AND OBJECTIVE: Copper is a metal element which plays a pivotal role in the pathology of various neurological disorders including COGNITIVE DISORDERS. Previous studies have shown different relationships between serum levels of copper and cognitive impairment. This study aimed to investigate the relationship between serum levels of copper and COGNITIVE DISORDERS in the ELDERLY in Amirkola.METHODS: This cross-sectional study is a part of Amirkola Health and Ageing Project performed on all the population is 60 years and older. According to the Mini-Mental State Examination (MMSE), people were divided into two groups with impaired cognitive status (N=347) and normal (N=657). People with cognitive impairment were classified in mild, moderate, severe subgroups. In this test, point more than or equal to 25 (30-25) was considered as natural and score less than 25 as a person with cognitive impairment. Serum copper level was measured in venous blood samples and was compared between two groups.FINDINGS: In this study, of 1616 ELDERLY people, 1004 people in the age group 60-90 years were examined. 518 men and 486 women were existed with a significant difference in SERUM LEVEL OF COPPER between the sexes (p<0.0001). The average SERUM LEVEL OF COPPER in people without cognitive impairment (129.43±54.83) was different from an average copper level in patients with cognitive impairment (135.06±57.38), but was not statistically significant. There was a significant difference in serum levels of copper in the MMSE subgroups (p=0.009).CONCLUSION: The results showed that cognitive impairment is associated with serum levels of copper.

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APA: Copy

KHEIRKHAH, F., HOSSEINI, S.R., AZADFORUZ, S., PARSIAN, H., REZAEE, H., MOAUDI, S., & BIJANI, A.. (2016). THE RELATIONSHIP BETWEEN SERUM COPPER LEVEL WITH COGNITIVE DISORDERS IN ELDERLY. AMIRKABIR, 18(10), 26-31. SID. https://sid.ir/paper/688676/en

Vancouver: Copy

KHEIRKHAH F., HOSSEINI S.R., AZADFORUZ S., PARSIAN H., REZAEE H., MOAUDI S., BIJANI A.. THE RELATIONSHIP BETWEEN SERUM COPPER LEVEL WITH COGNITIVE DISORDERS IN ELDERLY. AMIRKABIR[Internet]. 2016;18(10):26-31. Available from: https://sid.ir/paper/688676/en

IEEE: Copy

F. KHEIRKHAH, S.R. HOSSEINI, S. AZADFORUZ, H. PARSIAN, H. REZAEE, S. MOAUDI, and A. BIJANI, “THE RELATIONSHIP BETWEEN SERUM COPPER LEVEL WITH COGNITIVE DISORDERS IN ELDERLY,” AMIRKABIR, vol. 18, no. 10, pp. 26–31, 2016, [Online]. Available: https://sid.ir/paper/688676/en

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