مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

234
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

236
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

EVALUATION OF PRE-CLINICAL SAFETY AND TOXICOLOGY OF ALTHAEA OFFICINALIS EXTRACTS AS NATUROPATHIC MEDICINE FOR COMMON CARP (CYPRINUS CARPIO)

Pages

  613-629

Abstract

 The current study was done to investigate the preclinical safety and toxicology of Althaea officinalisextract as naturopathic medicine in COMMON CARP (Cyprinus carpio).Specimens were treated with 0 (control), 2.5, 5 and 10 g of MARSHMALLOW extract for 45 days. Plasma BIOCHEMICAL PARAMETERS were measured after 15 and 45 days. Total protein, albumin and globulin levels (p<0.05) were significantly higher in the fish fed with 10 gA. officinalis extract than that in control groups on day 45. Although, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) activities significantly decreased (p<0.05) in fish fed with A. officinalis extract on day 15. The use of theA. officinalis extract (10 g) led to a significant increase in AST, lactate dehydrogenase (LDH) and ALP activities and cholesterol levels on day 45 (p<0.05) and a significant decrease in plasma glucose and cholesterol levels on day 15 (p<0.05). There was no significant difference in glucose levels and creatine kinase (CK) activity between all treatments and the control group on day 45 (p>0.05). During the experimental period, triglyceride levels noticeably decreased in fish fed with 2.5 g ofA. officinalis extract (p<0.05). Although, administration of MARSHMALLOW extract up to 5 g per kg of feed did not show any side effect on fishes, the use of theA. officinalis extract (10 g) led to cytotoxicity and modifications in blood BIOCHEMICAL PARAMETERS of fish. Therefore, we recommend the use of the lower concentrations than 10 g A. officinalisextract in prospective clinical studies.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    SOLEIMANY, V., BANAEE, M., MOHISENI, M., NEMATDOOST HAGI, B., & MOUSAVI DEHMOURDI, L.. (2016). EVALUATION OF PRE-CLINICAL SAFETY AND TOXICOLOGY OF ALTHAEA OFFICINALIS EXTRACTS AS NATUROPATHIC MEDICINE FOR COMMON CARP (CYPRINUS CARPIO). IRANIAN JOURNAL OF FISHERIES SCIENCES, 15(2), 613-629. SID. https://sid.ir/paper/691599/en

    Vancouver: Copy

    SOLEIMANY V., BANAEE M., MOHISENI M., NEMATDOOST HAGI B., MOUSAVI DEHMOURDI L.. EVALUATION OF PRE-CLINICAL SAFETY AND TOXICOLOGY OF ALTHAEA OFFICINALIS EXTRACTS AS NATUROPATHIC MEDICINE FOR COMMON CARP (CYPRINUS CARPIO). IRANIAN JOURNAL OF FISHERIES SCIENCES[Internet]. 2016;15(2):613-629. Available from: https://sid.ir/paper/691599/en

    IEEE: Copy

    V. SOLEIMANY, M. BANAEE, M. MOHISENI, B. NEMATDOOST HAGI, and L. MOUSAVI DEHMOURDI, “EVALUATION OF PRE-CLINICAL SAFETY AND TOXICOLOGY OF ALTHAEA OFFICINALIS EXTRACTS AS NATUROPATHIC MEDICINE FOR COMMON CARP (CYPRINUS CARPIO),” IRANIAN JOURNAL OF FISHERIES SCIENCES, vol. 15, no. 2, pp. 613–629, 2016, [Online]. Available: https://sid.ir/paper/691599/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button