Optimization of antioxidant activity of Ferula persica by Ultrasound waves using various ratios of ethanol-water solvent at different temperatures whit Response Surface Methodology

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Estakhr P.; TAVAKOLI J.; BEIGMOHAMMADI F.; ALAEE SH.

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Journal: IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY Year:2019 | Volume:16 | Issue:91 Page(s): 291-303

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Title

Optimization of antioxidant activity of Ferula persica by Ultrasound waves using various ratios of ethanol-water solvent at different temperatures whit Response Surface Methodology

Author(s)

Estakhr P. | TAVAKOLI J. | BEIGMOHAMMADI F. | ALAEE SH. | Issue Writer Certificate

Keywords

Ferula persicaQ1

Ultrasound wavesQ2

Antioxidant ActivityQ1

OptimizationQ2

Response surface methodologyQ1

Abstract

In the present study, the Optimization process of phenolic compounds extraction and Antioxidant Activity (DPPH radical-scavenging assay, FRAP test, and oxidative stability index) of Ferula persica was evaluated using Ultrasound waves through Response surface methodology (RSM). To optimize the extraction process from the central composite design with three independent variables including time (5, 27. 5 and 50 minutes), temperature (25, 45 and 65 ° C) and ethanol ratio in water-ethanol solvent (0, 50 and 100% ) was used. In general, the results of analysis of variance showed that independent parameters had a significant effect on the DPPH radical-scavenging assay, FRAP test, and oxidative stability index of Ferula persica extract, their Correlation coefficients (R2) were 0. 91, 0. 94 and 0. 93, respectively. However, the proposed model for total phenolic compounds does not indicate the significant effect of these mention parameters. The results showed that the optimum conditions for Antioxidant Activity of Ferula persica extract were at 52. 9 ° C and 53. 5% ethanol concentration in water-ethanol solvent with 34. 1 minutes for sonication. It was also found that the experimental results were close to those predicted by the Response surface methodology. Evaluation of the Antioxidant Activity results of various extracts of Ferula persica showed that in most conditions, it has a suitable antioxidant power.

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APA: Copy

Estakhr, P., TAVAKOLI, J., BEIGMOHAMMADI, F., & ALAEE, SH.. (2019). Optimization of antioxidant activity of Ferula persica by Ultrasound waves using various ratios of ethanol-water solvent at different temperatures whit Response Surface Methodology. IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 16(91 ), 291-303. SID. https://sid.ir/paper/71694/en

Vancouver: Copy

Estakhr P., TAVAKOLI J., BEIGMOHAMMADI F., ALAEE SH.. Optimization of antioxidant activity of Ferula persica by Ultrasound waves using various ratios of ethanol-water solvent at different temperatures whit Response Surface Methodology. IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY[Internet]. 2019;16(91 ):291-303. Available from: https://sid.ir/paper/71694/en

IEEE: Copy

P. Estakhr, J. TAVAKOLI, F. BEIGMOHAMMADI, and SH. ALAEE, “Optimization of antioxidant activity of Ferula persica by Ultrasound waves using various ratios of ethanol-water solvent at different temperatures whit Response Surface Methodology,” IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, vol. 16, no. 91 , pp. 291–303, 2019, [Online]. Available: https://sid.ir/paper/71694/en

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