مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Evidence of jaagsiekte sheep retrovirus-induced pulmonary adenocarcinoma in Ouled Djellal breed sheep in Algeria

Pages

  93-95

Abstract

 We report the occurrence of lung cancer in a six months old lamb of Ouled Djellal breed from Algeria. The main clinical sign was a considerable amount of whitish foamy fluid discharge from the nostrils when the animal head was lowered and the rear end was lifted. The postmortem examination revealed the presence of enlarged, heavy and edematous lungs with diffuse or foci areas, reddish or white-gray in color. The gross and histological lesions of the lungs were compatible with Pulmonary adenocarcinoma. Lung adenocarcinoma in Sheep is caused by jaagsiekte Sheep Retrovirus (JSRV) and originated from differentiated alveolar type II cells and non-ciliated bronchiolar epithelial Clara cells. We evidenced the expression of the oncogenic JSRV by immunostaining of lung slides with specific antibodies against the JSRV envelope. The viral proteins were expressed only in the tumor cells from the affected areas. As already described in other countries, JSRV-induced lung adenocarcinoma is present in the Sheep population in Algeria.

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    • Cite

    APA: Copy

    Sid, Nassim, Bennoune, Omar, Ouhida, Soraya, Heras, Marcelo De Las, & Leroux, Caroline. (2020). Evidence of jaagsiekte sheep retrovirus-induced pulmonary adenocarcinoma in Ouled Djellal breed sheep in Algeria. VETERINARY RESEARCH FORUM, 11(1), 93-95. SID. https://sid.ir/paper/781540/en

    Vancouver: Copy

    Sid Nassim, Bennoune Omar, Ouhida Soraya, Heras Marcelo De Las, Leroux Caroline. Evidence of jaagsiekte sheep retrovirus-induced pulmonary adenocarcinoma in Ouled Djellal breed sheep in Algeria. VETERINARY RESEARCH FORUM[Internet]. 2020;11(1):93-95. Available from: https://sid.ir/paper/781540/en

    IEEE: Copy

    Nassim Sid, Omar Bennoune, Soraya Ouhida, Marcelo De Las Heras, and Caroline Leroux, “Evidence of jaagsiekte sheep retrovirus-induced pulmonary adenocarcinoma in Ouled Djellal breed sheep in Algeria,” VETERINARY RESEARCH FORUM, vol. 11, no. 1, pp. 93–95, 2020, [Online]. Available: https://sid.ir/paper/781540/en

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