NUMERICAL MODELING OF CEREBRAL AUTOREGULATION IN HUMAN COMMON CAROTID ARTERY

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SIRI S.; NABAEI M.; FATOURAEE N.

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Paper Information

Journal: IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING Year:2015 | Volume:9 | Issue:3 Page(s): 229-241

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Information Journal Paper

Title

NUMERICAL MODELING OF CEREBRAL AUTOREGULATION IN HUMAN COMMON CAROTID ARTERY

Author(s)

SIRI S. | NABAEI M. | FATOURAEE N. | Issue Writer Certificate

Keywords

LUMPED PARAMETER MODELQ2

FLUID-STRUCTURE INTERACTIONQ2

CEREBRAL ARTERYQ2

SHEAR STRESSQ2

ARTERIAL VASODILATION AND VASOCONSTRICTIONQ2

Abstract

Every organ has its own metabolic and functional requirements and needs a variable amount of blood; hence, auto regulation is an important phenomenon. SHEAR STRESS induced autoregulation is defined as the innate ability of an organ to keep its hemodynamic conditions stable against changes in heart rate and perfusion pressure. For example, when heart rate changes arterial vessels undergo vasodilation or vasoconstriction in order to stabilize the hemodynamic forces and stresses with respect to the flow needed.The current study examines the local mechanisms employed in automatic control. Local regulatory mechanisms function independently of external control mechanisms, such as sympathetic nerves and endocrine hormones. Therefore, they can be considered isolated mechanisms.The application of boundary conditions in numerical modeling is of utmost importance, hence, using arterial tree modeling to achieve appropriate boundary conditions seems necessary. Thus, we have presented a zero-dimensional (lumped parameter) extensive model first. Then, we used this model to achieve boundary conditions for the common carotid artery. As one of the most important hemodynamic parameters, SHEAR STRESS regulation will then be modeled in an axisymmetric model of this artery.

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APA: Copy

SIRI, S., NABAEI, M., & FATOURAEE, N.. (2015). NUMERICAL MODELING OF CEREBRAL AUTOREGULATION IN HUMAN COMMON CAROTID ARTERY. IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING, 9(3), 229-241. SID. https://sid.ir/paper/81670/en

Vancouver: Copy

SIRI S., NABAEI M., FATOURAEE N.. NUMERICAL MODELING OF CEREBRAL AUTOREGULATION IN HUMAN COMMON CAROTID ARTERY. IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING[Internet]. 2015;9(3):229-241. Available from: https://sid.ir/paper/81670/en

IEEE: Copy

S. SIRI, M. NABAEI, and N. FATOURAEE, “NUMERICAL MODELING OF CEREBRAL AUTOREGULATION IN HUMAN COMMON CAROTID ARTERY,” IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING, vol. 9, no. 3, pp. 229–241, 2015, [Online]. Available: https://sid.ir/paper/81670/en

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