Simulation of Nano-Particle Mediated Hyperthermia inside Homogeneous Tissue in External Magnetic Field

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NAZARI MOHAMMAD; Solgi Razieh; Graily Ghazale; MAHDAVI SEYED RABI; SHIRAZI ALIREZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING Year:2018 | Volume:12 | Issue:1 Page(s): 11-23

Download Full-Text

Persian Verion

View:

749

Download:

Cites:

Information Journal Paper

Title

Simulation of Nano-Particle Mediated Hyperthermia inside Homogeneous Tissue in External Magnetic Field

Author(s)

Keywords

SimulationQ2

COMSOLQ1

Magnetic Nano-ParticleQ1

HyperthermiaQ1

Abstract

In clinical studies, it is difficult to determine the temperature distribution throughout both tumor and normal tissue during Hyperthermia treatment, since temperatures are sampled at only a limited number of locations with conventional sensors. Simulation studies can help physicians understand better the effects of the treatment. In this study, three 2D tumor models are built in the COMSOL software environment based on the images of nano-particle distributions in sliced PC3, DU145 and LAPC4 tumors. The images are pre-processed in MATLAB before being imported into COMSOL. A uniform distribution model is added as a control group. Temperature distribution, maximum temperature, time to reach steady state, CEM43, iso-effective dose and heat flux at tumor-tissue boundary are analyzed to evaluate the effect of the nano-particle distribution on Hyperthermia treatment. The results indicate that a more concentrated nano-particle distribution is better in damaging diseased tissue than the uniform distribution under high heating power. A more uniform distribution is better than the concentrated distribution under low heating power. For concentrated nano-particle distributions, the location where the nano-particles are concentrated influences tissue damage: a more centered one has a better effect. Tumor tissue is more likely to be defective.

Cites

No record.

References

No record.

Cite

APA: Copy

NAZARI, MOHAMMAD, Solgi, Razieh, Graily, Ghazale, SHIRAZI, ALIREZA, & MAHDAVI, SEYED RABI. (2018). Simulation of Nano-Particle Mediated Hyperthermia inside Homogeneous Tissue in External Magnetic Field. IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING, 12(1 ), 11-23. SID. https://sid.ir/paper/81707/en

Vancouver: Copy

NAZARI MOHAMMAD, Solgi Razieh, Graily Ghazale, SHIRAZI ALIREZA, MAHDAVI SEYED RABI. Simulation of Nano-Particle Mediated Hyperthermia inside Homogeneous Tissue in External Magnetic Field. IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING[Internet]. 2018;12(1 ):11-23. Available from: https://sid.ir/paper/81707/en

IEEE: Copy

MOHAMMAD NAZARI, Razieh Solgi, Ghazale Graily, ALIREZA SHIRAZI, and SEYED RABI MAHDAVI, “Simulation of Nano-Particle Mediated Hyperthermia inside Homogeneous Tissue in External Magnetic Field,” IRANIAN JOURNAL OF BIOMEDICAL ENGINEERING, vol. 12, no. 1 , pp. 11–23, 2018, [Online]. Available: https://sid.ir/paper/81707/en

Related Journal Papers