HISTOLOGIC AND HISTOMORPHOMETRIC CHANGES OF TESTIS FOLLOWING ORAL EXPOSURE TO METHYL TERTIARY-BUTYL ETHER IN ADULT RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHOLAMI S.; ANSARI LARI M.; KHALILI L.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR) Year:2015 | Volume:16 | Issue:3 (52) Page(s): 288-292

Download Full-Text

Persian Verion

View:

679

Download:

156

Cites:

Information Journal Paper

Title

HISTOLOGIC AND HISTOMORPHOMETRIC CHANGES OF TESTIS FOLLOWING ORAL EXPOSURE TO METHYL TERTIARY-BUTYL ETHER IN ADULT RAT

Author(s)

GHOLAMI S. | ANSARI LARI M. | KHALILI L. | Issue Writer Certificate

Keywords

HISTOMORPHOMETRICQ2

MTBEQ2

RATQ2

TESTISQ3

Abstract

Methyl tertiary-butyl ether (MTBE) is used to reduce carbon monoxide and ozone in urban air and to boost fuel octane. There is a lack of knowledge in the literature about the HISTOMORPHOMETRIC changes of the TESTIS following exposure to MTBE. Therefore, this experimental study was performed to determine the effect of oral exposure to MTBE on histologic and HISTOMORPHOMETRIC changes of TESTIS in adult RAT. A total of 25 adult male Sprague-Dawley RATs were randomly divided into five equal experimental groups: control, almond oil and three treatment groups which received 400, 800 and 1600 mg/kg/day MTBE in almond oil by gavages for 30 consecutive days. HISTOMORPHOMETRIC analysis showed no significant difference in absolute and relative TESTIS weight, connective tissue thickness, germinal epithelium height, tunica albuginea thickness and Sertoli cell numbers between experimental groups (P>0.05). However, trend analysis showed that the seminiferous tubule diameter increased and interstitial cell numbers as well as spermatocyte and spermatid cell numbers decreased significantly in MTBE treated groups (P<0.05). It may be concluded that MTBE could exert adverse effects on spermatogenic cells in adult RAT. Whether the observed changes in the present study are due to the direct effect of MTBE via passing blood-testis barrier or its indirect effect through another mechanism should be elucidated in future studies.

Cites

No record.

References

No record.

Cite

APA: Copy

GHOLAMI, S., ANSARI LARI, M., & KHALILI, L.. (2015). HISTOLOGIC AND HISTOMORPHOMETRIC CHANGES OF TESTIS FOLLOWING ORAL EXPOSURE TO METHYL TERTIARY-BUTYL ETHER IN ADULT RAT. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), 16(3 (52)), 288-292. SID. https://sid.ir/paper/85744/en

Vancouver: Copy

GHOLAMI S., ANSARI LARI M., KHALILI L.. HISTOLOGIC AND HISTOMORPHOMETRIC CHANGES OF TESTIS FOLLOWING ORAL EXPOSURE TO METHYL TERTIARY-BUTYL ETHER IN ADULT RAT. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR)[Internet]. 2015;16(3 (52)):288-292. Available from: https://sid.ir/paper/85744/en

IEEE: Copy

S. GHOLAMI, M. ANSARI LARI, and L. KHALILI, “HISTOLOGIC AND HISTOMORPHOMETRIC CHANGES OF TESTIS FOLLOWING ORAL EXPOSURE TO METHYL TERTIARY-BUTYL ETHER IN ADULT RAT,” IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), vol. 16, no. 3 (52), pp. 288–292, 2015, [Online]. Available: https://sid.ir/paper/85744/en

Related Journal Papers