The reporting of suspicious transactions, emphasized in Recommendation 20 of the FATF, is considered the cornerstone of the fight against money laundering, and the success of all anti-money laundering measures depends on it. Therefore, the present study employs a descriptive-analytical approach with the aim of familiarizing the reader with the requirements for reporting suspicious transactions related to money laundering and examines the legal, jurisprudential, and executive obstacles that impede the reporting of suspicious transactions. In conclusion, the study investigates the position of Iran in comparison with global standards and highlights the most significant legal, jurisprudential, and executive challenges facing the reporting of suspicious transactions. The findings indicate that in the anti-money laundering regulations of Iran, especially in the amended law on combating money laundering ratified in 2018 and its executive directive of Article 14 ratified in 2019, necessary measures have been taken in line with international standards to report suspicious transactions, and the necessary structures have been established. However, professional secrecy rules, the principle of validity, Presumption of possession, policies related to capital attraction in banks, and high compliance costs with anti-money laundering standards may overshadow this important principle in the fight against money laundering and may cause disruption in the desirable path of reporting suspicious transactions.