The variation in pressure on various faces of a rectangular shaped tall building due to the presence of courtyard and openingis examined for a boundary layer flow condition corresponding to terrain category II of IS: 875 (Part 3)-2015. ANSYSCFX is used for the simulation. Two turbulence models, k- and shear stress transport (SST), are used in the validation ofANSYS CFX, and the results are compared with different international standards. In the presence of courtyard and opening, interesting and unusual pressure distributions on certain faces are observed due to a self-interference effect. Flow patternsaround the building for different areas of opening are also studied to explain the phenomena occurring around the building. Furthermore, the polynomial expressions for calculating force coefficients and mean pressure coefficients of each face fordifferent angles of attack and areas of opening are proposed using least-squares regression method. Accuracy of the fittedpolynomials is measured by R2 value.