Considering that the main way for fungi and bacteria to enter livestock and poultry breeding centers and finally to the human food chain is food, so accurate information about the amounts of Escherichia coli and Salmonella fungi and bacteria in meat meal samples and animal, poultry and aquatic feed is essential to control them. In this study, fungal counting tests, Escherichia coli bacterial counts and Salmonella counts were performed from waste centers (meat meal) and livestock, poultry and aquaculture factories in different parts of Fars city. A total of 40 samples (20 samples of meat meal, 20 samples of prepared feed) weighing approximately 1500 grams were taken.In order to investigate the contamination of samples with different fungi by the method of counting fungi according to the national standard of Iran, to count the bacterium Escherichia coli according to the national standard of Iran No. 3456 and to identify Salmonella by the method of searching Salmonella in food according to the national standard of Iran. 1810 was used. The results of this study showed that out of 40 samples, one mushroom contaminated feed sample (2.5%), one Escherichia coli contaminated feed sample (2.5%) and three samples (one feed sample and two meat meal samples) Salmonella infection (7.5%) was positive. This indicates that hygienic protocols are performed in livestock and poultry feed factories and slaughterhouses in Fars province to prevent the infection of feed and meat meal with fungi, Salmonella and Escherichia coli