Counter-urbanization has been defined with many definitions in research literature as increasing of the small town population in the process of urban expansion and development. This study investigates the counter-urbanization process in Isfahan metropolitan area based on an exploratory method using the population and immigration data, diurnal commuting, and the immigration motivators. The results show that, during different periods, population growth has been changed from the greater cities’ metropolitan area to the small towns. So that, there is less population growth near the main greater cities during the last decade. Regarding the immigration as well as migration effectiveness over the population, and immigration motivators, it can be said that the most important parameters of small towns’ expansion near the greater cities are better habitation opportunities, and finding better jobs. Furthermore, decreasing the diurnal commuting close to the greater cities shows that small towns, which are farther from the greater city, have more autonomy. In addition, based on polarization reversal model, and population development investigation in metropolitan areas, there are population development from the greater cities’ centre to the periphery area, which is leaded to decrease the population of the main greater city, and increase the population absorption in small towns. Consequently, the urbanization of Isfahan metropolitan area has entered to a counter-urbanization phase.

As a part of the human society, children have formed the future generation of every country, and the child's interaction with the surrounding environment requires his physical and mental development. Therefore, it is important to pay attention to the environment that promotes mental and physical development of the child. In order to check the suitable environment for children, the initiative of the child-friendly city has been taken into consideration. The general purpose of this research is to improve the status of two cities from the perspective of a child-friendly city and to identify the appropriate indicators of a child-friendly city and to make a comparative comparison in the two metropolises of Tehran and Isfahan. The current research is developmental in terms of the combined method and in terms of the goal, and it is based on library and documentary studies, field surveys and interviews. Yeoman-Whitney test was used to analyze the indicators. The results of the evaluation show that in the comparison of the two cities of Tehran and Isfahan in terms of the examined indicators (social and physical, economic, environmental, urban management and leisure), Tehran city in the variable of safety and protection with an average of 3.09 and Isfahan city in Participation and citizenship variables with an average of 3.22 have a favorable level. Although Tehran is in a better condition compared to Isfahan in other indicators, in general, both cities are far apart in terms of standard indicators, and suggestions have been made in this regard.

ABSTRACT The purpose of this research is to compile effective scenarios for improving the resilience of new Habitations in Isfahan. This research is applied in terms of purpose and in terms of method; it is a combination of documentary and survey methods and future research. Investigations have shown that based on possible situations, 10,040 scenarios have been identified to study the resilience of new Habitations in the Metropolitan Isfahan Isfahan against the risk of earthquakes. Of these scenarios, 9999 weak scenarios, 36 high compatibility or believable scenarios and 5 strong scenarios have been identified. Thirty-six scenarios with high compatibility can be divided into four groups according to their proximity, and each group includes several scenarios with almost common characteristics despite the small difference in one or more situations among the 15 key factors. These four groups represent the general framework of the situations governing the future resilience of the studied habitations. According to the results of the examination of different groups of scenarios in this research, scenario number 1 in the first group of scenarios has been introduced as a favorable scenario due to having favorable and complete conditions. Also, among the key factors studied, the collective justice factor, with an average of -4 and a total score of -144, is the most critical key factor in the studied scenarios   Extended Abstract Introduction The inability to accurately predict the future, as well as the complexities of increasing change, has led researchers to take advantage of the emerging knowledge of future studies and bring the issue of foresight into the heart of planning activities and to predict scientific and technological developments.The appropriate effectiveness of today's decision-making is related to recognizing the future situation and how planners deal with it. Accurate knowledge of the future also depends on a suitable method for discovering the future. Today, with traditional planning methods, including outsourcing in the past, it is unlikely to generate reliable foresight in the medium and long term. Futuristic science approaches in planning to find the key factors and drivers of development in the planning space emphasize that in this way, the planner with the lever of control and management of the future to plan optimally for the future. In the urban area of Isfahan, the evolution of industry has played an important role in changing the economic structure and the emergence of a new hierarchy of residential areas and population concentration, especially in Isfahan. In order to overcome the problems caused by urban development, especially to reduce the housing problem and prevent population explosion, reduce the destruction of agricultural land, preserve the cultural texture and control construction, new habitations in Isfahan Metropolitan have been thought and built. Existence of numerous problems and issues, such as active faults with the ability to cause extensive human and financial losses, construction of high-level units outside the rules, weakness of infrastructure services such as medical centers, transportation, etc., extensive migration from inside and outside the province to these habitations, the establishment of heavy industries around these habitations, regardless of the characteristics of the structure, the high age of the building in some of the studied habitations, etc., has increased attention to the issue of resilience in these habitations. Given the importance of futurism has a significant impact on reducing the human and financial losses of human habitations, the question has been raised: What is the most desirable scenario to improve the resilience of new urban habitations in the Isfahan Metropolitan?   Methodology The present research is applied in terms of purpose and in terms of nature, based on the new method of futurology, analytical-structural. Interaction / structural analysis is a method for analyzing the possible occurrence of an issue in a predicted set. Judgments about the potential for interaction between the predicted topics can adjust the probabilities of this. In this study, using 87 variables in the form of 6 dimensions, the interaction of the studied variables has been analyzed, and finally, using the identified key factors, scenarios affecting the resilience of new urban habitations in Isfahan urban area have been developed.   Results and discussion In this research, 54 possible situations have been proposed for 15 key factors. The number of states of selected key factors is between 3-4 possible states for each factor. From a total of 540 possible situations in the table of scenarios with high compatibility in this research, 99 favorable situations (18.33 percent), 69 static situations (12.78 percent), 124 situations on the verge of crisis (22.96 percent), and 248 crises (93.45 percent). The results of the application of Scenario Wizard software in this research have shown that there are 10040 scenarios for studying the resilience of new habitations in Isfahan urban area against the risk of earthquakes, and it is possible to use this number of extracted scenarios to forecast the resilience of the studied habitations. It is not acceptable, and they can only be used statistically. The extracted scenarios can be categorized into three general sections as scenarios with strong compatibility, weak scenarios, and incompatible scenarios. Out of the 10040 scenarios obtained in this research, 9999 weak scenarios, 36 incompatible scenarios and 5 strong scenarios have been identified. In order to determine the optimal scenario among the strong scenarios, an action has been taken. According to the conditions governing the 3 mentioned scenarios, scenario number 1 can be introduced as the optimal scenario in this research because it has 100% suitable conditions.   Conclusion According to the grouping of compatible scenarios, selecting the best scenario from 3 scenarios should be done. As mentioned in the previous topics, the scenarios of the second and third groups cannot be considered and cited due to having many problems; therefore, they should be removed from the review cycle at this stage. The only remaining group of scenarios is the first group, or the group of golden scenarios, which is in the best condition in terms of desirability. Since there is only one scenario in the golden scenario group, scenario number 1 of this research can be introduced as a favorable scenario for the resilience foresight of new urban habitations in the Isfahan Metropolitan. By examining the situation of scenario number 1 in the table of compatible scenarios, this result has been obtained that out of 15 situations, the development of geographical perspectives, increasing the level of awareness about the seismicity of the place of residence, identifying and dealing with dangerous factors, population density of 0-70 people, improving the level of social participation of citizens, increasing the level of social justice among citizens, the dynamism and development of economic and social activities, the development of intellectual and financial support for economic activities, the development of social capital, the improvement of the level of compensation capacities, the greater role of people compared to centers government during an earthquake, reducing damage caused by an earthquake, improving the level of performance of city managers during an earthquake, having a strong urban information bank and a large urban distribution have 100% favorability.   Funding There is no funding support.   Authors’ Contribution Authors contributed equally to the conceptualization and writing of the article. All of the authors approved thecontent of the manuscript and agreed on all aspects of the work declaration of competing interest none.   Conflict of Interest Authors declared no conflict of interest.   Acknowledgments  We are grateful to all the scientific consultants of this paper.

To investigate the effect of vermicompost, N fertilizer and their integration on growth, biological and essential yields oil and its components in two populations (Varamin and Isfahan), an experiment was conducted in a randomized complete block design with three replications in the field of Isfahan Medicinal Plants Research Center in 2016. Fertilizer treatments including 100% urea, vermicompost 33.3 and urea 66.6%, vermicompost 66.6 and urea 33.3%, 100% vermicompost and control treatment (without fertilizer) as the first factor and Varamin and Isfahan populations as the second factor were selected. The results showed that the interaction effects of nitrogen fertilizer and populations on all studied traits were significant. In both populations, nitrogen fertilizer improved height, biological and essential oil yields, content of essential oil compounds (d-Carvone and its yield, α-phellandrene and linalool; except p-Cymene and Limonene in Isfahan population). Since in medicinal plants, the quantity (biological yield) and quality (essential oil and d-Carvone; the most important ingredient and the highest amount of essential oil in this experiment), 66.6% vermicompost + 33.3% urea in Varamin population, was the best treatment in the experiment. In addition an in the direction of human health and sustainable agriculture, it is possible to reduce 33% of chemical fertilizers application and pollution; however, in terms of other essential oil contents (α-phellandrene, Linalool and p-Cymene), 100% vermicompost fertilizer treatment was superior in Isfahan population.

Background: Radiation therapy is one of the primary treatment methods for breast cancer. Oral and pharyngeal complications are significant challenges associated with this treatment. This study aimed to compare the oral and pharyngeal complications in patients receiving radiation therapy using two techniques: conventional and hypofractionated.Methods: In this cross-sectional analytical study, 70 breast cancer patients treated at Seyed-al-Shohada Hospital in Isfahan in 2024 were examined. The patients were divided into two groups: those receiving conventional radiation therapy (5000 cGy in 25 fractions) and those undergoing hypofractionated radiation therapy (4250 cGy in 16 fractions). Oral and pharyngeal complications were assessed and compared during treatment and up to 60 days post-treatment based on the CTCAE V5 criteria in both groups.Findings: The findings of this study demonstrated a significantly higher incidence of acute oral and pharyngeal adverse events in the conventional radiotherapy group compared to the hypofractionated radiotherapy group (P = 0.05). Specifically, the prevalence of moderate (grade 2) and severe (grade 3) adverse events was 17.1% and 8.5% in the conventional group, respectively, compared to 14.2% and 0% in the hypofractionated group. Data analysis indicated that the clinical variables of age, body mass index (BMI), and concurrent chemotherapy also had a significant impact on the severity of oral and pharyngeal adverse events in both treatment groups (P < 0.05).Conclusion: This clinical study demonstrated that patients receiving hypofractionated radiation therapy experienced fewer oral and pharyngeal complications than those treated with the conventional technique.

Background: This study aimed to evaluate blood lead levels in patients with age-related macular degeneration (AMD).Methods: This case-control study was conducted on patients with AMD and healthy controls at Ahvaz, Khozestan, Iran. The control group was randomly selected from the general outpatient clinic. Two groups were matched for the following parameters: age, sex, smoking, lipid profiles, past vascular diseases, and history of ophthalmic surgery.Findings: Ninety-five AMD patients (55.8% male, mean age 69.93 ± 10.17 years) and 95 controls (31.6% male, mean age 65.50 ± 7.65 years) were enrolled. The mean blood lead level in the case and control groups was 25.70 ± 10.08 and 24.25 ± 9.74 µg/dL, respectively (P = 0.46). Also, after adjusting for confounding factors, there was no significant difference between the two groups' blood lead levels (P = 0.4).Conclusion: No significant differences were found in the blood lead levels, indicative of short-term exposure, between patients with AMD and the control group.