Rhabdomyolysis is a common condition with potentially devastating complications, and only few therapeutic options are available for the treatment of acute Rhabdomyolysis. In this case, a 56-year-old male who had been drinking alcohol, presented to the emergency department for evaluation of slurred speech, ataxic gait, mood instability, and cognitive disorder. On admission, his creatine kinase (CK) level was 2882 U/L. Despite aggressive fluid repletion, his CK level continued to increase, peaking at 11350 U/L. On administration and after the fluid transfusion with isotonic saline, his CK levels and clinical symptoms improved dramatically. We report this case as it is a rare condition of rhabdomyolysis due to alcohol, with the intent to highlight its clinical features and paraclinical finding.

Statins are commonly used drugs in the treatment of hyperlipidemia (HL), despite some undesirable side effects. These range from mild symptoms such as myopathy, muscle weakness and myalgia to severe muscle weakness associated with chronic myopathy and acute renal failure (ARF) as a result of rhabdomyolysis. The most serious and deadly side effect of statins is rhabdomyolysis. The case presented here is of a patient with rhabdomyolysis due to treatment with the antihyperlipidemic drug, atorvastatin.

Introduction: Some studies have reported creatinine phosphokinase (CPK) as a new emergingway in predicting the outcomes of poisoned patients. This study aimed to evaluate the association of serum CPK level in the first 24 hours with outcomes of poisoned patients. Methods: This retrospective cross-sectional study was performed using the medical profiles of poisoned patients aged between 13 and 70 years old who were referred to the emergency department of a big referral medical toxicology center during 6 years and whose necessary data for this study was available. Results: 318 patients with the mean age of 34. 9§ 14. 5 years were studied (77. 1% male). The mean serum CPK level of patients was 4693. 1 § 10303. 8 (35– 89480) IU/L. There was no significant correlation between serum CPK level and cause of poisoning (r= 0. 16; p=0. 51), age (r =-0. 021; p = 0. 651), sex (r = 0. 131; p = 0. 281), seizure (r =-0. 022; p = 0. 193), level of consciences (r =-0. 138; p = 0. 167), and duration of hospital stay (r= 0. 242, p = 0. 437). The mean serum CPK level was significantly higher in ICU admitted (p<0. 0001), AKI (p<0. 0001), hyperkalemia (p<0. 0001), hypophosphatemia (p=0. 045), and hypocalcaemia (p=0. 008) cases. The best cut off point of serum CPK level in predicting acute kidney injury (AKI) was estimated to be 10000 IU/L (sensitivity = 83. 8% and specificity = 68. 8%). Conclusion: It seems that CPK could be considered as a candidate tool for screening the intoxicated patients in need for ICU admission and at risk for AKI.

Introduction: Rhabdomyolysis can be a symptom of COVID-19, with very few cases described so far. AKI and renal failure following rhabdomyolysis are a potentially dangerous complication. Diagnosis of rhabdomyolysis in COVID-19 is difficult due to overlap.Materials and Method: The present study was a PICO review that examined rhabdomyolysis in COVID-19. The documents browsed by Google Scholar, Sid and Mag Iran databases were analyzed using the keywords rhabdomyolysis, creatine kinase, COVID-19, acute renal failure.Results:  Rhabdomyolysis following COVID-19 and SARS-CoV-2 reports of viral contamination of striated muscle may result in muscle destruction. Rhabdomyolysis in COVID-19 is a late complication. Evaluation of CK and myoglobin levels is important for the diagnosis of rhabdomyolysis in COVID19 patients. The mechanism of rhabdomyolysis in COVID-19 is unknown and various mechanisms are used.Conclusion: Rhabdomyolysis may cause acute kidney damage (AKI). Prompt diagnosis is a prerequisite for successful treatment and prevention of complications.