CONGRESS OF WOUND AND TISSUE REPAIR | Year:2016 | دوره:3 |Papers Count:128

THIS STUDY AIMED TO SYSTEMATICALLY ASSESS THE PARAMETER-SPECIFIC EFFECTS OF LOW-LEVEL LASER THERAPY (LLLT) ON THE WOUND HEALING PROCESS. DESPITE DIVERSE METHODS BEING APPLIED TO INDUCE WOUND HEALING, MANY WOUNDS REMAIN RECALCITRANT TO ALL TREATMENTS. PHOTOBIOMODULATION INVOLVES INDUCING WOUND HEALING BY ILLUMINATING WOUNDS WITH LIGHT EMITTING DIODES OR LASERS. ALTHOUGH LLLT USED ON DIFFERENT IN VITRO, ANIMAL MODELS, AND CLINICAL TRIAL, WOUND HEALING IS INDUCED BY MANY DIFFERENT WAVELENGTHS AND POWERS, BUT AT THIS TIME NOT CLARIFIED OPTIMAL SET OF LLLT PARAMETERS IDENTIFIED.

THE DEVELOPMENT OF NEW METHODS TO IMPROVE SKIN WOUND HEALING MAY AFFECT THE OUTCOMES OF MEDICAL CONDITIONS. WE EVALUATE THE MOLECULAR, CELLULAR AND CLINICAL EFFECTS OF PLANT COMPOUNDS ON WOUND HEALING. APPLICATION OF NATURAL INGREDIENTS AND HERBS FOR TREATING ULCERS HAS BEEN IN THE HISTORY OF HUMAN LIFE.

BACKGROUND: ELECTRICAL STIMULATION IS DESCRIBED AS A SAFE NONINVASIVE AND POSSIBLE EFFECTIVE INTERVENTION TO ACCELERATE WOUND HEALING. THIS IS AN EASY TO USE METHOD MAY HELP HEALING PROCESS IN WOUNDS, SPECIFICALLY WOUNDS AT RISK OF COMPROMISED HEALING. THIS REVIEW HELPS TO CRITICALLY EVALUATE RESULTS OF THE RELEVANT QUALIFIED TRIALS AND EFFECTIVENESS OF DIFFERENT ELECTRICAL STIMULATION MODALITIES ON DELAYED WOUND HEALING OR WOUNDS AT RISK OF NONUNION...

NOWADAYS, MEDICINE IS RAPIDLY MOVING TOWARDS THE DEVELOPMENT OF NON-INVASIVE TREATMENTS AND PERSONALIZED STRATEGIES TO ACHIEVE A MORE PREDICTABLE AND OPTIMAL TISSUE REGENERATION. SEVERAL PROCEDURES ARE PERFORMED IN AN ATTEMPT TO REGENERATE LOST TISSUES AND ENHANCE THE HEALING PROCESS.

SULFUR MUSTARD (2, 2-DICHLORODIETHYL SULFIDE: SM), THE PROTAGONIST OF VESICANT CHEMICAL WEAPONS, WAS FIRST USED IN JULY 1917. DESPITE PROHIBITION OF ITS PRODUCTION AND USE BY INTERNATIONAL CONVENTIONS, IT HAS BEEN USED IN SEVERAL CONFLICTS. MORE THAN 100, 000 SOLDIERS AND CIVILIANS WERE INJURED DUE TO SM EXPOSURE DURING IRAN-IRAQ WAR (1980-1988). THE ACUTE SKIN LESIONS CONSIST OF ERYTHEMA, EDEMA, AND BLISTERS.

BACKGROUND: PRESSURE ULCER DEVELOPMENT IS A NEGATIVE POINT FOR HEALTH CARE SYSTEMS IN THE WORLD. FIRSTH STEP IN PREVENTION OF PRESSURE ULCER IS IDENTIFYING RISK FACTORS OF PRESSURE ULCER. ONE GROUP OF PATIENTS THAT ARE AT HIGH RISK OF PRESSURE ULCER DEVELOPMENT IS WHO ARE UNDER OPEN HEART CARDIAC SURGERY. HOWEVER STUDY ABOUT THIS GROUP OF PATIENTS IS VERY LIMITED. IN PRESENT STUDY WE, EXAMINED RELATIONSHIP BETWEEN THE RISK OF PRESSURE ULCER DEVELOPMENT IN THIS GROUP OF PATIENTS AND HEMODYNAMIC PARAMETERS.

BACKGROUND: PSEUDOMONAS AERUGINOSA IS WIDELY DISTRIBUTED IN NATURE AND IS CONSIDERED AS AN OPPORTUNIST PATHOGEN FOR HUMAN. INCREASE IN ANTI-BIOTIC RESISTANCE AND THE EMERGENCE OF TREATMENT RESISTANT STRAINS IS ONE OF THE MOST IMPORTANT CHALLENGES IN TREATMENT OF PSEUDOMONAS AERUGINOSA INFECTIONS IN BURN PATIENTS. THIS STUDY AIMS TO EVALUATE THE ANTIMICROBIAL EFFECT OF LACTOBACILLUS GASSERI ON PSEUDOMONAS AERUGINOSA ISOLATED FROM CLINICAL SAMPLES OF BURN PATIENTS...

BACKGROUND: ONE IMPORTANT COMPLICATION OF DIABETES MELLITUS IS CHRONIC, NON-HEALING DIABETIC FOOT ULCERS (DFUS). ALTHOUGH MANY NEW DRESSINGS ARE AVAILABLE FOR DFUS CARE IN IRAN, VERY FEW HIGH-LEVEL TRIALS HAVE BEEN CONDUCTED THAT COMPARE THESE DRESSING TO DETERMINE WHICH WILL PROVIDE THE BEST LEVEL OF CARE CLINICALLY. CONSIDERING THE SIGNIFICANT RESULTS OF THE NEW BIODEGRADABLE AND BIOCOMPATIBLE DRESSINGS IN THE FIELD OF WOUND HEALING, WE ASSESSED TO COMPARE THE CLINICAL EFFICACY AND ACCEPTABILITY OF ACTICOAT™, CHITOSAN-BASED BIOCOMPATIBLE DRESSING (IPPISKIN DRESSING) AND AMNION DRESSING FOR DFI WOUND.

THERE ARE VAST VARIOUS RESOURCES OF EXTREMELY LOW FREQUENCY MAGNETIC FIELDS IN THE ENVIRONMENT OF HUMAN BEINGS SUCH AS POWER LINES, MOBILE PHONES, EARTH, ETC. DURING THE LAST DECADE, BEING EXPOSED TO THESE NATURAL AND ARTIFICIAL RESOURCES OF EXTREMELY LOW FREQUENCY (ELF) MAGNETIC FIELDS HAS BECOME UNAVOIDABLE FOR HUMAN BEINGS...

HIDRADENITIS SUPPURATIVA (HS) IS A PAINFUL, CHRONIC AND RECURRENT INFLAMMATORY SKIN DISORDER AFFECTS PATIENT IN THEIR MOST PRODUCTIVE TIME OF LIFE. IT IMPOSES DIRECT AND INDIRECT COSTS TO HEALTHCARE SYSTEM (MEHDIZADEH, 2015). THE PREVALENCE OF HS RANG FROM<1% TO 4% IN DIFFERENT POPULATIONS (JEMEC, 2012). THE IMPACT OF HS ON PATIENT’S QUALITY OF LIFE AND WORK PRODUCTIVITY IS EXTENSIVE AND YET REMAINS UNDERSTUDIED AND UNDERESTIMATED (ALAVI, 2015)...

MODERN DRESSINGS INCREASE THE WOUND-HEALING RATE RATHER THAN JUST TO COVER IT. HYDROGEL DRESSING CAN PROTECT INJURED SKIN AND KEEP IT APPROPRIATELY MOIST TO SPEED THE HEALING PROCESS. PROPOLIS IS A NATURAL PRODUCT THAT MEETS THE REQUIREMENTS AS FUNCTIONAL ADDITIVE FOR WOUND DRESSING DUE TO ITS ANTIMICROBIAL ACTIVITIES...

BACKGROUND: BURN INJURIES RESULT IN LOSS OF ITS PROTECTIVE FUNCTION THAT LEADING TO A HIGH RISK OF INFECTION. RESULTS DERIVED FROM SEVERAL STUDIES INDICATE THAT BONE MARROW MESENCHYMAL STEM CELLS (BMSC) MAY CONTRIBUTE TO TISSUE REGENERATION WHETHER THROUGH PRODUCING VARIETY OF BIOACTIVE GROWTH...

BACKGROUND: EPISIOTOMY AFTER CUTTING THE UMBILICAL CORD AT BIRTH IS THE MOST COMMON SURGICAL PROCEDURE.THE FOLLOWING BENEFITS ARE THE ROUTINE EPISIOTOMY, SEVERE PERINEAL LACERATION, FETAL TRAUMA AND URINARYSTRESS REDUCING. NEVERTHELESS, SOME STUDIES HAVE SHOWN THAT THIS SURGERY HAD NO BENEFIT FOR THE MOTHER AND RESULT IN UNNECESSARY PAIN PERINEAL REGION, INCONTINENCE OF URINE AND FECES, HEMATOMA, INFECTION, AND DAMAGE TO THE WOUND REGION. THIS STUDY AIMED TO EVALUATE THE EPISIOTOMY WOUND INFECTION IN MOTAHARI HOSPITAL OF URMIA WAS CONDUCTED IN 1394...

NON- HEALING ARE A SIGNIFICANT PROBLEM FOR HEALTH CARE SYSTEM AND PATIENTS ALL OVER THE WORLD.1-1.5 % OF THE POPULATION IN INDUSTRIALIZED COUNTRIES HAVE A WOUND.WOUND TREATMENT COST BETWEEN 2-4 % OF HEALTH CARE BUDGET AND DUE TO DEMOGRAPHIC CHANGES AND RISE IN DIABETES, CHRONIC WOUNDS WILL INCREASE...

PROPOLIS IS A NATURAL PRODUCT THAT MEETS THE REQUIREMENTS AS FUNCTIONAL ADDITIVE FOR WOUND DRESSING DUE TO ITS ANTIMICROBIAL ACTIVITIES. IN THIS WORK, ETHANOLIC PROPOLIS EXTRACT (EPE) LOADED CORN STARCH (EPE/CS) WERE SUCCESSFULLY PREPARED USING CASTING OF EPE/CS BLEND SOLUTION, AND CHARACTERIZATIONS WITH RESPECT TO THEIR MECHANICAL PROPERTIES...

IATROGENIC ULCERS ARE COMPLICATIONS THAT OCCUR AS A RESULT OF MEDICAL TREATMENT BY PHYSICIANS OR OTHER MEMBERS OF THE HEALTH CARE TEAM. THE CAUSES AND SEVERITY OF IATROGENIC INJURIES VARY, BUT IN SEVERE WOUND CASES, CONSULTING A PLASTIC SURGEON FOR WOUND TREATMENT MAY BE WARRANTED...

IN THE ABSENCE OF MICROVASCULAR REPLANTATION OR IN CRASH INJURY CASES IN WHICH OBTAINING AN ACCEPTABLE FUNCTION IS NOT POSSIBLE, AMPUTATION OF THE INJURED FINGER SEEMS TO BE THE BEST TREATMENT MODALITY. SOME STUDIES RECOMMENDED LEECH THERAPY FOR THIS KIND OF INJURY AFTER VASCULAR REPAIR TO DECREASE VENOUS CONGESTION.

BACKGROUND: INJURED TISSUE IS REPAIRED IN THE PROCESS OF WOUND HEALING. WITHOUT ANY PROGRESSIVE TREATMENTS, IT LASTS A LONG TIME TO COMPLETELY HEAL AND IN SOME PATIENTS WOUNDS DO NOT RESPOND TO THE STANDARD THERAPY. SOME STRESS CAN MODULATE THIS PROCESS.

BACKGROUND: THERMAL BURNS ARE STILL AMONG MAJOR PROBLEMS WITH LOCAL AND SYSTEMIC CONSEQUENCES.ITS MORBIDITY AND MORTALITY BEARS HIGH FINANCIAL COST ON HEALTH SYSTEMS IN EACH COUNTRY. HYPERBARIC OXYGEN THERAPY (HBOT) IS A SOPHISTICATED TREATMENT MODALITY; 100% OXYGEN IS PRESCRIBED AT PRESSURES GREATER THAN ATMOSPHERIC PRESSURE IN SPECIAL CHAMBERS. HBOT HAS MANY MEDICAL INDICATIONS INCLUDING THERMAL BURNS BUT UNKNOWN IN MANY COUNTRIES.

NONINVASIVE IMAGING APPROACHES CAN PROVIDE GREATER INFORMATION ABOUT A WOUND THAN VISUAL INSPECTION DURING THE WOUND HEALING AND TREATMENT PROCESS. HERE WE WOULD LIKE TO FOCUS ON VARIOUS NONINVASIVE OPTICAL IMAGING TECHNIQUES DEVELOPED TO IMAGE DIFFERENT WOUND ESPECIALLY SUPERFICIAL TYPES...

WHEN BURN VICTIMS NEED A SKIN GRAFT THEY TYPICALLY HAVE TO GROW SKIN ON OTHER PARTS OF THEIR BODIES, A PROCESS THAT CAN TAKE WEEKS. A NEW TECHNIQUE USES STEM CELLS DERIVED FROM THE UMBILICAL CORD TO GENERATE NEW SKIN MUCH MORE QUICKLY.

BACKGROUND: ANAL FISSURE IS THE MOST COMMON ANORECTAL DISEASE IN ALL SEX AND AGE FISSURES DEVELOPED TO ANAL STENOSIS. CHRONIC DISEAS THAT DO NOT RESPOND TO DRUG TRAPY MUST BE SURGERY. IN THIS STUDY REVIEW HAS BEEN PERUSED THE RESULT AND COMPLICATIONS OF OPEN SPHINCTEROTOMY AND CLOSED SPHINCTEROTOMY...

DIABETIC FOOT ULCERS IN DIABETIC PATIENTS IS ONE OF THE MOST COMMON PROBLEMS AND FAILURE TO PROVIDE A SOLUTION TO MAKE THE DISEASE HAS BECOME A HUGE PROBLEM. LOW LEVEL LASERS HAVE A GOOD IMPACT ON OPEN WOUNDS AND INJURIES AIM OF THIS STUDY WAS TO EVALUATE THE EFFECT OF LOW LEVEL LASER THERAPY ON DIABETIC ULCERS.

BACKGROUND: UNCONTROLLED DIABETES MELLITUS CAN LEAD TO COMPLICATED INFECTED FOOT ULCERS THAT HAVE ALL NEGATIVE FACTORS FOR HEALING. ALTHOUGH DEBRIDEMENT AND THEN PROPER COVERAGE IS A CLASSIC APPROACH, THESE ULCERS ARE ACCOUNTED CHALLENGING FOR A SURGEON BECAUSE OF ONGOING INFECTION AND POORLY VASCULARIZED TISSUES TO TRANSFER.THIS LED TO APPLICATION OF LESS INVASIVE APPROACH TO REDUCE THE SECONDARY SURGICAL INJURY BY MINIMAL DEBRIDEMENT AND IMPLICATION OF MODALITIES LIKE MAGGOT THERAPY, VACUUM ASSISTED CLOSURE, BIOLOGIC DRESSING AND OTHERS.

IN THE LAST YEARS, THE HEALTH-CARE SERVICES HAVE REGISTERED WORLDWIDE AN INCREASED NUMBER OF PATIENTS SUFFERING FROM CHRONIC WOUNDS AND ULCERS. CURRENT STRATEGIES TO TREAT CHRONIC WOUNDS OFFER LIMITED RELIEF TO THE 7.75 MILLION PATIENTS...

NOWADAYS, THERE IS A GROWING TENDENCY FOR THE USE OF NATURAL PRODUCTS IN TREATMENTS OF BURN INJURIES, AS PEOPLE CONSIDER THEM MORE SAFE. PROBIOTICS ARE LIVING MICRO-ORGANISMS THAT MAY HAVE BENEFITS ON HUMAN HEALTH. PREVIOUS STUDIES SHOWED THAT, LACTIC ACID BACTERIA, AS A GROUP OF PROBIOTICS, MAY HAVE BENEFICIAL EFFECTS ON THE SKIN HEALTH. MOREOVER, THE BENEFITS OF TOPICAL USE OF SOME STRAINS OF PROBIOTIC BACTERIA ON THE WOUND HEALING HAVE BEEN SHOWN IN PREVIOUS RESEARCHES.BECAUSE, THE EFFECTS OF PROBIOTICS IS STRICTLY STRAIN DEPENDENT, IN THE CURRENT STUDY, THE EFFECTS OF LACTOBACILLUS ACIDOPHILUS ON THE SECOND DEGREE BURN WOUNDS WAS STUDIED IN THE RATS.

THANKS TO THE BENEFICIAL IMPACT OF DECADES OF BIOETHICS, REGENERATIVE MEDICINE CLINICAL TRIALS INVOLVING HUMAN PARTICIPANTS IS HIGHLY REGULATED AND SUBJECT TO PRECISE ETHICAL CONSIDERATIONS.THE PRIORITY OF ALMOST ALL OF ETHICAL CODES IS ON PROTECTION OF PARTICIPANTS AGAINST HARM THAT MIGHT RESULT FROM RESEARCH...

BACKGROUND: DURING DERMAL WOUND HEALING, FIBROBLASTS NEED TO MIGRATE INTO, AND PROLIFERATE WITHIN THE WOUND SITE. ACCELERATED MIGRATION OF FIBROBLAST ACROSS THE SKIN LESION DURING DERMAL WOUND HEALING PROFOUNDLY AFFECT THE HEALING PROCESSES. THE EFFECTS OF DIFFERENT CONCENTRATIONS OF CURCUMINON ON PROLIFERATION, MIGRATION AND COLLAGENESIS OF FIBROBLAST IN RELATION WITH WOUND HEALING PROCESS WERE EXPLORED IN VITRO.

BACKGROUND: BURN IS ONE OF HEALTH PROBLEMS THAT HUMANKIND HAS BEEN ENCOUNTERED WITH IN THE HISTORY. NOW, SILVER SULFADIAZINE, AS AN ANTIBACTERIAL AGENT, IS THE DRUG THAT PREFERENTIALLY USED FOR TREATMENT OF BURN WOUNDS....

STEM CELL THERAPY HAS EMERGED AS A PROMISING NEW APPROACH IN ALMOST EVERY MEDICINE SPECIALTY. THIS VAST, HETEROGENEOUS FAMILY OF CELLS ARE NOW BOTH NATURALLY (EMBRYONIC AND ADULT STEM CELLS) OR ARTIFICIALLY OBTAINED (INDUCED PLURIPOTENT STEM CELLS OR IPSCS) AND THEIR FATES HAVE BECOME INCREASINGLY CONTROLLABLE, THANKS TO ONGOING RESEARCH IN THIS PASSIONATE NEW FIELD.

BACKGROUND: CHRONIC WOUNDS ARE WOUNDS THAT TAKE A LONG TIME TO HEAL, DO NOT HEAL, OR RECUR; THESE WOUNDS ARE OFTEN ULCERS ASSOCIATED WITH DIABETES OR ARTERIAL OR VENOUS DISEASE (POOR BLOOD CIRCULATION) AND PRESSURE ULCERS. ONE CHARACTERISTIC OF CHRONIC WOUNDS IS THAT THE WOUND TISSUES ARE HYPOXIC (HAVE LOW OXYGEN LEVELS). CHRONIC WOUNDS ARE COMMONLY OCCURRING AND REDUCE THE QUALITY OF LIFE OF THOSE AFFECTED AND ARE SIGNIFICANT SOCIOECONOMIC PROBLEM...

THROUGHOUT HISTORY, THERE HAVE BEEN MANY ADVANCES MADE IN WOUND MANAGEMENT. RESEARCH ON NEW MODALITIES TO ENHANCE WOUND HEALING IS ONGOING AT MOST MEDICAL CENTERS. ONE SUCH MODALITY IS LASER IRRADIATION. LASER IRRADIATION AS A PHOTOTHERAPEUTIC MEANS FOR THE STIMULATION AND/OR ACCELERATION OF WOUND HEALING BEGAN IN THE 1970S BY MESTER AND COLLEAGUES. IN THE PAST TEN YEARS LASER DIODES MOSTLY HAVE BEEN USED COMPARED TO OTHER LASERS IN WOUND HEALING.

KELOIDS AND HYPERTROPHIC SCARS ARE A CHALLENGING PROBLEM IN PLASTIC AND RECONSTRUCTIVE SURGERY. THESE ABNORMAL PROCESSES ARE BENIGN FIBROUS OVERGROWTHS OF SCAR TISSUE, WHICH RESULTS FROM AN ABNORMAL RESPONSE TO TRAUMA...

AS TIMES GOES BY, NEW ASPECTS OF BIOLOGICALLY DRIVEN CONCEPTS OF HEALING PROCESSES AND FACTORS AFFECTING THIS COMPLEX PHENOMENA SHOW UP. NOT ONLY THE MEDIATORS AND CHEMICAL FACTORS- AS WERE THOUGHT BEFORE- BUT SURPRISINGLY, THE GEOMETRICAL AND 3D SPACES CAN APPARENTLY INFLUENCE THE TREATMENT OUTCOMES...

BACKGROUND: DIABETES IS A SERIOUS CHRONIC DISEASE IN THE WORLD, ESPECIALLY IN MIDDLE EAST AND IRAN. IT IS ASSOCIATED WITH SERIOUS COMPLICATIONS IF IT IS NOT CONTROLLED. IT CAN LEAD TO AMPUTATION OF THE FOOT, REDUCED QUALITY OF LIFE AND EVEN MORTALITY.

DATA FROM THE UNITED STATES INDICATE THAT CHRONIC WOUNDS AFFECT AROUND 6.5 MILLION PATIENTS WITH AN ESTIMATED US$25 BILLION ANNUAL EXPENDITURE ON THEIR TREATMENT. WOUND HEALING IS A COMPLEX, DYNAMIC PROCESS REQUIRED FOR MAINTAINING HOMEOSTASIS IN AN ORGANISM. BESIDES MANY BIOLOGICAL AND PHARMACEUTICAL METHODS BEING INVESTIGATED...

SKIN LOSS PRESENTS AN ONGOING CHALLENGE IN RECONSTRUCTIVE SURGERY. APPROACHES TO ACHIEVE TENSION FREE CLOSURE OF THESE DEFECTS INCLUDE AUTOLOGOUS SKIN FLAPS, ALLOPLASTIC AND XENOGENIC IMPLANTS. HOWEVER, THESE APPROACHES HAVE DISADVANTAGES...

HUMAN KERATINOCYTES COULD BE USED IN THE REPAIR OF DAMAGED SKIN, IN TISSUE ENGINEERING APPLICATIONS, GENE THERAPY AND RECENTLY, THE GENERATION OF IPS CELLS. WE ISOLATED HUMAN KERATINOCYTES FROM FORESKIN AND SUBSEQUENTLY CULTURED THEM ON FIBRONECTIN...

NON-HEALING CUTANEOUS WOUNDS ARE THE RISING HEALTH THREAT AND ECONOMIC ISSUE FOR SOCIETY AND PATIENT’S FAMILY AS THERE ARE 7 MILLION VICTIMS OF CHRONIC WOUNDS CREATING AN ECONOMIC BURDEN OF>50 BILLION USD PER YEAR ONLY IN USA AND APPROXIMATELY 37 MILLION SKIN WOUNDS GLOBALLY.

BACKGROUND: ETHNOMEDICINAL PLANTS HAVE BEEN IDENTIFIED AND PRESCRIBED ALL OVER HUMAN HISTORY. PLANTS MAKE MANY CHEMICAL COMPOUNDS THAT ARE FOR BIOLOGICAL FUNCTIONS, INCLUDING WOUND HEALING, AND DEFENCE AGAINST FUNGI AND BACTERIA...

BIOFILMS ARE INVOLVED IN APPROXIMATELY 80% OF HUMAN INFECTIONS. THE EFFICIENCY OF PHOTODYNAMIC THERAPY (PDT) AS A NEW TECHNIQUE TO TREAT BIOFILMS CAN BE ENHANCED BY VARIOUS NANOTECHNOLOGY PLATFORMS.HERE WE AIMED TO IMPROVE THE EFFICACY OF PDT FOR BACTERIAL BIOFILMS USING DIFFERENT NANOSYSTEMS (NANOPHOTOSENSITIZERS)...

BACKGROUND: MAGGOT DEBRIDEMENT THERAPY (MDT) IS INTRODUCED AS ONE OF THE BEST TREATMENT OPTION FOR VARIOUS KINDS OF CHRONIC WOUNDS. THE PATIENTS WITH CHRONIC WOUNDS MAY SUFFER MANY SIDE COMPLICATIONS SUCH AS KIDNEY DISORDER. THE COMPLICATED DISORDERS OF PATIENTS WITH DIABETIC MELLITUS MAY LEAD TO FAIL THE TREATMENT APPROACHES. THE AIM OF THIS SURVEY WAS TO STUDY EFFECTIVENESS OF MDT ON PATIENTS WITH DIABETIC MELLITUS WHO SUFFER SUCH COMPLICATED DISORDERS.

IN OUR COUNTRY LIKE WHOLE THE WORLD, ONE OF THE IMPORTANT PROBLEMS IN OUR PATIENTS IS “WOUND OPTIMAL MANAGEMENT”. THERE IS SOME WOUND CARE CLINIC IN THE CITIES WHICH ARE CENTER OF PROVINCES. THESE CLINICS ARE ONLY IN BIG CITIES. THE TEAM WHO WORK IN THESE CLINICS ARE HEALTH CARE PROFESSIONALS CONSISTS OF NURSES, PHYSICIANS WHO HAVE DIFFERENT ESPECIALITY: ENDOCRINOLOGISTS, DERMATOLOGIST, GENERAL SURGEON INFECTIOUS DISEASE SPECIALIST...

YOUNG FIBROBLASTS CAN PROLIFERATE MORE THAN AGED CELLS, AND SECRETION OF EXTRACELLULAR MATRIX (ECM) PROTEINS IS LOWER IN THE SKIN OF OLD PEOPLE. RECENTLY, DIFFERENT LOW-TEMPERATURE PLASMA DEVICES HAVE BEEN DEVELOPED; HOWEVER THEIR DETAILED FUNCTIONS ARE UNCLEAR. WE EXAMINED THE EFFECT OF COLD ATMOSPHERIC PLASMA (CAP) ON HUMAN AND MOUSE FIBROBLAST CELLS IN VITRO AND ON WOUND HEALING IN VIVO.

CHONDROITINASE ABC I (CABC I) IS A KEY AND IMPORTANT ENZYME FOR CURING SPINAL CORD INJURIES THAT CLEAVES GLYCOSAMINOGLYCAN CHAINS. CABC I IN DAMAGED NERVOUS TISSUE FACILITATES AXON REGENERATION.STABILIZATION OF ENZYME COULD IMPROVE ITS PERFORMANCE...

BACKGROUND: PRESSURE ULCERS ARE A SIGNIFICANT PROBLEM FOR PATIENTS AND HEALTH CARE PROVIDERS WORLDWIDE.CARDIAC ESPECIALLY POST CARDIAC OPERATIVE PATIENTS, BECAUSE OF HAVING MORE RISK FACTORS THAN OTHER PATIENTS, ARE AT EXTREMELY HIGH RISK OF PRESSURE ULCERS. USING A STANDARD RISK ASSESSMENT TOOL AND PAYING ATTENTION TO THE MAIN RISK FACTORS OF PRESSURE ULCER AND UPDATING KNOWLEDGE AND PRACTICE IN PREVENTION AND MANAGEMENT CAN BE A USEFUL METHOD FOR IDENTIFYING THE HIGH-RISK PATIENTS IN ADMISSION IN ORDER TO PREVENT THEM FROM DEVELOPING SUCH ULCERS. INTERDISCIPLINARY PRESSURE ULCER PREVENTION TEAM CAN IDENTIFY HIGH RISK PATIENTS AND CONTROL OR MANAGE THEM CORRECTLY.

BACKGROUND: TISSUE ENGINEERING AND REGENERATIVE MEDICINE HAS BEEN CONSIDERED AS AN INTERDISCIPLINARY FIELD, WHICH OPENED NEW ERA FOR TREATING PATIENTS WITH GENITOURINARY DISORDERS.THE FIELD OF UROLOGIC TISSUE ENGINEERING HAS BEEN APPROACHED TO MAINTAIN NORMAL URINARY/SEXUAL FUNCTION AND PRESERVE FERTILITY. THE AIM OF THIS SPEECH IS TO PRESENT THE RESULTS OF TISSUE AND ORGAN DECELUULARIZATION TECHNIQUES AND FOCUS ON THE APPLICATIONS OF ACELLULAR DERMAL MATRIX ALLOGRAFT (ADMA) FOR LOWER GENITOURINARY TRACT RECONSTRUCTION FOLLOWING SOPHISTICATED QUALITY CONTROL DURING THE LAST TWO DECADES AT OUR CENTER...

FIBROBLASTS USED IN TISSUE ENGINEERING MAY BE ALLOGENEIC OR AUTOLOGOUS. IN CONTRAST TO ALLOGENEIC CELLS, AUTOLOGOUS FIBROBLASTS CARRY NO RISK OF REJECTION OR RISK OF CROSS-INFECTION. HOWEVER, THERE IS OFTEN A DELAY IN CULTURING AUTOLOGOUS CELLS IN ORDER TO OBTAIN SUFFICIENT CELL NUMBERS, WHEREAS ALLOGENEIC CELLS ARE CRYOPRESERVED AND THEREFORE READILY AVAILABLE. FOR PERMANENT ENGRAFTMENT, AUTOLOGOUS FIBROBLASTS ARE NECESSARY.

BACKGROUND: DUE TO HARD-TO-TREAT RESPONSE, THE DIABETIC FOOT ULCER IS AMONG THE COMMON PROBLEMS IN COMPLICATIONS OF TYPE 2 DIABETES. MORBIDITY AND HIGH COST OF TREATING THESE INJURIES IMPOSE A SIGNIFICANT BURDEN ON INDIVIDUAL AND COMMUNITY HEALTH SYSTEM...

DESPITE THE PROGRESS MADE IN THE TREATMENT OF WOUNDS, BUT THERE ARE STILL PROBLEMS IN THE TREATMENT OF VARIOUS WOUNDS. PROBLEMS SUCH AS INFECTION, AMPUTATION, PROLONGED WOUND HEALING, PAIN AT THE WOUND SITE AND OTHER PROBLEMS. ACCORDING TO DOCUMENTS THAT THERE IS HONEY IN WOUND TREATMENT AND IT IS POINTED OUT IN THE OLD AND NEW TEXTS. IN THIS STUDY, THE USE OF HONEY IN WOUND HEALING, HARMS AND BENEFITS OF HONEY WAS CHECKED. ALSO HONEY WAS COMPARED WITH OTHER TREATMENT IN WOUND TREATMENT...

MULTIPLE SCLEROSIS (MS) IS AN INFLAMMATORY DEMYELINATING DISORDER OF CENTRAL NERVOUS SYSTEM (CNS). POLYPHENOL CURCUMIN HAS BEEN USED IN TRADITIONAL MEDICINE AS AN EFFECTIVE DRUG FOR A VARIETY OF DISEASES. DIFFERENT FORMULATIONS OF CURCUMIN ARE INTRODUCED TO INCREASE ITS STABILITY AND EFFECTIVENESS...

BACKGROUND: AUTOLOGOUS CHONDROCYTE IMPLANTATION (ACI) IS A BIOMEDICAL TREATMENT THAT REPAIRS DAMAGES IN ARTICULAR CARTILAGE. ACI PROVIDES PAIN RELIEF WHILE AT THE SAME TIME SLOWING DOWN THE PROGRESSION OR CONSIDERABLY DELAYING PARTIAL OR TOTAL JOINT REPLACEMENT (KNEE REPLACEMENT) SURGERY. THE GOAL OF ACI IS TO ALLOW PEOPLE SUFFERING FROM ARTICULAR CARTILAGE DAMAGE TO RETURN TO THEIR OLD LIFESTYLE; REGAINING MOBILITY, GOING BACK TO WORK AND EVEN PRACTICING SPORTS AGAIN...

MANY OF THE HUMAN SOCIETIES (ABOUT 1%) HAVE SOME PROBLEMS ABOUT WOUND. WOUND HEALING ALWAYS IS A CONCERN FOR HUMAN AND MANY ECONOMIC AND SOCIAL COSTS HAS IMPOSED IN HUMAN SOCIETY.REGARDLESS OF THE SOURCE AND CAUSE OF WOUND, PRINCIPALLY IF OTHER FACTORS SUCH AS DIABETES AND WOUND INFECTION IS HIGHER...

BACKGROUND: ETHNOMEDICINAL PLANTS HAVE BEEN IDENTIFIED AND PRESCRIBED ALL OVER HUMAN HISTORY. PLANTS MAKE MANY CHEMICAL COMPOUNDS THAT ARE FOR BIOLOGICAL FUNCTIONS, INCLUDING WOUND HEALING, AND DEFENCE AGAINST FUNGI AND BACTERIA. THE MEDICINAL PLANTS ARE USED WIDELY BECAUSE OF THEIR EFFECTIVENESS, FEWER SIDE EFFECTS AND RELATIVELY LOW COST. CITRUS LIMON IS A MEDICINALLY USEFUL FRUIT WITH MANY REMEDIAL PROPERTIES...

BACKGROUND: CUSTOM MOLDED OFFLOADING INSOLE AND REMOVABLE PLUG INSOLE APPEAR TO BE BENEFICIAL FOR REDUCE PLANTAR PRESSURE IN PATIENTS WITH FORE FOOT DIABETIC FOOT ULCER (DFU). HOWEVER, QUANTITATIVE EVIDENCE OF PRESSURE REDUCTION BY MEANS OF CUSTOM MOLDED OFFLOADING INSOLE AND REMOVABLE PLUG INSOLE IS LIMITED. THE VALUE OF ADDITIONAL INSOLE ACCESSORIES, SUCH AS HEEL CUP WITH MEDIAL ARCH ADDITIONS, HAS NOT BEEN TESTED.

BACKGROUND: THE THERAPEUTIC MANAGEMENT OF SEVERE BURNS REMAINS A CHALLENGING TOPIC. RESULTS DERIVED FROM SEVERAL STUDIES INDICATE A BENEFIT FOR TISSUE REGENERATION BY STIMULATED MESENCHYMAL STEM CELLS (SMSCS) WITH LPS OR POLY-I-C CELLS. THE AIM OF THIS STUDY WAS TO INVESTIGATED THE EFFECTS OF SMSCS WITH COMPOUND LPS AND POLY-I-C AT THE SAME TIME ON BURN HEALING AND COMPARED WITH SMSCS JUST WITH POLY-I-C.

BACKGROUND: 20-30% 0F ADULT POPULATION HAVE EXPERIENCES OF TEMPOROMANDIBULAR JOINT DISORDER. IT SEEMS THAT REFERRAL PERSISTENT PAIN IS THE MOST IMPORTANT CAUSE IN TREATMENT OF 90% OF PATIENTS. COMMON THERAPEUTIC METHODS TO REDUCE PAIN AND DISFUANCTION OF TMJ ARE: DRUGS, OCCLUSAL APPLIENCES, PHYSICAL THERAPY AND STRESS CONTROL...

BACKGROUND: LIMBAL STEM CELL DEFICIENCY (LSCD) CAN DEVELOP IN TRAUMATIC, IMMUNOLOGIC, OR GENETIC DISEASES THAT AFFECT THE OCULAR SURFACE. LSCD LEADS TO CONJUNCTIVALIZATION, WITH CORNEAL VASCULARIZATION AND OPACIFICATION AND SUBSEQUENT LOSS OF VISION THUS LIMBAL STEM CELL TRANSPLANTATION IS A TREATMENT WAY FOR THIS PROBLEM OUR AIM WAS EVALUATE OF EFFICIENCY LSCT IN TREATMENT OF HUMAN CORNEA DESTRUCTION.

SKIN IS A COMPLEX TISSUE, WHICH COMPRISES MULTIPLE LAYERS. AN INJURY TO THIS STRATIFIED STRUCTURE IS CONSIDERED TO BE THE BEGINNING OF A SEQUENCE OF EVENTS DESIGNED TO RESTORE SKIN INTEGRITY. DEPENDING ON THE DIAMETER AND SEVERITY OF A WOUND, DELETERIOUS PHYSIOLOGICAL AND METABOLIC CHANGES CAN OCCUR, LEADING TO IMPAIRED WOUND HEALING AND INCREASED MORBIDITY AND MORTALITY...

THE HUMAN BODY IS CAPABLE OF IMPRESSIVE ACTS OF SELF-WOUND HEALING. IT USES FOUR MAJOR COMPONENTS INCLUDING: 1- FIBRIN COMPACT MATRIX AS NATURAL EFFICIENT SCAFFOLD FOR EXPANSION OF NEW GENERATING TISSUE...

NOW A DAY’S USAGE OF STEM CELL IS MAIN FACTOR FOR REPAIRING IN THE MEDICAL FIELD; RESEARCHERS HAVE SPECIALCONSIDERATION ON THIS ASPECT.

BACKGROUND: BEDSORES THAT ALSO CALLED PRESSURE ULCERS ARE INJURIES TO THE SKIN AND UNDERLYING TISSUE RESULTING FROM PROLONGED PRESSURE ON THE AFFECTED AREA. AN ESTIMATED FIVE PERCENT OF ALL HOSPITALIZED PATIENTS DEVELOP AT LEAST ONE PRESSURE ULCER. PEOPLE WITH THE MOST RISK FACTOR OF BEDSORES ARE THOSE WITH A MEDICAL CONDITION THAT LIMITS THEIR ABILITY TO CHANGE POSITIONS, REQUIRES THEM TO USE A WHEELCHAIR OR CONFINES THEM TO STAY ON BED FOR A LONG TIME...

BACKGROUND: CHRONIC WOUNDS ARE OFTEN RESISTANT TO TREATMENT AND A GREAT CHALLENGE TO THE DEVELOPMENT OF INFECTIONS. DEBRIDEMENT IS DEFINED AS THE REMOVAL OF FOREIGN MATERIAL AND NECROTIC TISSUE FROM A WOUND AND IT CAN ALSO HELP TO STIMULATE WOUND HEALING. HOWEVER, NOT ALL METHODS OF DEBRIDEMENT ARE THE SAME. EACH METHOD HAS ADVANTAGES AND DISADVANTAGES THAT MUST BE CLEARLY UNDERSTOOD...

CLINICAL STUDIES HAVE SHOWN LOW ENERGY LASERS TO BE EFFECTIVE TO ACCELERATE THE HEALING OF INJURED TISSUE.ALTHOUGH THE BENEFICIAL EFFECTS OF LASER PHOTO STIMULATION ARE NOW GENERALLY ACCEPTED, THE MECHANISMS BY WHICH LASER LIGHT FACILITATES WOUND HEALING AND TISSUE REPAIR ARE NOT CLEARLY UNDERSTOOD.THE OBJECTIVE OF THIS PAPER WAS TO REVIEW AND BETTER UNDERSTANDING THE ROLE OF LOW-INTENSITY LASER IN THE PROGRESSION OF TISSUE HEALING...

BACKGROUND: WOUND HEALING IS AN INTEGRATED CELLULAR AND BIOCHEMICAL PROCEDURE OF RESTORING INDIGENOUS STRUCTURE FUNCTIONS OF VICIOUS TISSUE. HEALING IS A NORMAL PHENOMENON BY WHICH BODY ITSELF DOMINATE THE DAMAGED TO THE TISSUE BUT THE RATE OF HEALING IS VERY GRADUAL AND CHANCE OFMICROBIAL INFECTION IS VAST.

BREAST CANCER IS THE MOST COMMON CANCER AMONG WOMEN WORLDWIDE. ALTHOUGH SKIN INVOLVEMENT IS AN UNCOMMON PRESENTATION OF BREAST CANCER, THE SKIN CAN BE AFFECTED IN DIFFERENT STEPS OF BREAST CANCER MANAGEMENT. SKIN ULCERS, SKIN EDEMA, AND SKIN MASSES CAN BE SEEN AS THE INITIAL PRESENTATIONS OF THE IMPORTANT DISEASE. AS SOON AS THE DIAGNOSIS OF BREAST CANCER IS MADE BASED ON SKIN ULCERS, CHEMOTHERAPY WOULD PLAY THE FIRST AND ESSENTIAL ROLE IN THE MANAGEMENT OF THE ADVANCED DISEASE...

WOUND HEALING IS A BIOCHEMICAL PROCESS OF RESTORING NORMAL STRUCTURE FUNCTIONS OF DAMAGED TISSUE.WOUND HEALING IS A NATURAL FUNCTION BY WHICH BODY ITSELF OVERCOME THE DAMAGED TO THE TISSUE BUT THE RATE OF HEALING IS SLOW AND RATE OF MICROBIAL INFECTION IS HIGH. THE USE OF HERBAL DRUGS IS INCREASING IN DEVELOPED AS WELL AS DEVELOPING COUNTRIES BECAUSE THEY ARE SAFER AND WELL TOLERATED AS COMPARED TO THOSE ALLOPATHIC DRUGS. IN THIS PAPER, WE EXAMINED THE EFFECT OF HERBAL MEDICINE IN THE TREATMENT OF WOUNDS.MATERIALS AND METHODS: STUDY IS REVIEW ARTICLE THAT FOR IT HAVE BEEN USED A LOT OF RECENT PAPERS ABOUT WOUND HEALING WITH MEDICINAL PLANTS FROM REPUTABLE SITES INSTANCE GOOGLE SCHOLAR, PUBMED, SCOPUS AND ELSE.

REDUCING THE SCAR TO A MINIMUM IN SURGICAL OPERATIONS, ESPECIALLY COSMETIC SURGERIES, ARE CONSIDERED TO BE ONE OF THE MOST IMPORTANT CHALLENGES OF THE SURGEONS...

WOUND HEALING IS AN EXTREMELY INTRICATE AND HIGHLY DYNAMIC PROCESS. HIGH THROUGHPUT MOLECULARSCREENING TECHNOLOGIES SUCH AS DNA MICROARRAYS HOLD GREAT POTENTIAL IN ENHANCING OUR UNDERSTANDING OF COMPLEX BIOLOGICAL PROCESSES...

BACKGROUND: HEALING IS A NORMAL PHENOMENON BY WHICH BODY ITSELF DOMINATE THE DAMAGED TO THETISSUE BUT THE RATE OF HEALING IS VERY GRADUAL AND CHANCE OF MICROBIAL INFECTION IS VAST. RECOVERY IN HEALING PROCEDURE CAN BE PERFORM EITHER SHORTEN THE TIME REQUIRED FOR HEALING OR TO MINIMIZE THE UNDESIRED CONSEQUENCES...

WOUND HEALING OUTCOME IS REGULATED BY A FINE BALANCE BETWEEN DEPOSITION AND DEGRADATION OF EXTRACELLULAR MATRIX (ECM). OVER HEALING FORMATION SUCH AS KELOID IS MEDIATED BY EXAGGERATED ECM DEPOSITION AND ABNORMALITIES IN ECM DEGRADATION.

BACKGROUND: A CHRONIC WOUND IS ONE IN WHICH HEALING FAILS TO PROCEED THROUGH AN ORDERLY AND TIMELY PROCESS TO PRODUCE ANATOMIC AND FUNCTIONAL INTEGRITY, OR PROCEED THROUGH THE REPAIR PROCESS WITHOUT ESTABLISHING A SUSTAINED ANATOMIC AND FUNCTIONAL RESULT...

HYPERBARIC OXYGEN THERAPY (HBOT) IS A SHORT-TERM, HIGH DOSE OXYGEN INHALATION AND DIFFUSION THERAPY, DELIVERED SYSTEMATICALLY THROUGH AIRWAYS AND BLOOD UNDER HIGH PRESSURE BY USING HYPERBARIC CHAMBERS...

RECENTLY, THERE HAS BEEN A SUBSTANTIAL INCREASE IN THE VOLUME OF PUBLISHED WORK REGARDING THE PSYCHOSOCIAL ISSUES IN WOUND CARE, BUT WE ARE STILL ONLY SCRATCHING THE SURFACE OF UNDERSTANDING THE WAYS IN WHICH PSYCHOSOCIAL ELEMENTS IMPACT HEALING OR AFFECT THE WAYS IN WHICH INDIVIDUALS COPE WITH LONG-TERM WOUND RELATED PROBLEMS...

CURRENTLY AVAILABLE TREATMENTS FOR CHRONIC WOUNDS ARE INADEQUATE. A CLEARLY EFFECTIVE THERAPY DOES NOT EXIST, AND TREATMENT IS OFTEN SUPPORTIVE. THIS IS LARGELY BECAUSE THE CELLULAR AND MOLECULAR PROCESSES UNDERLYING FAILURE OF WOUND REPAIR ARE STILL POORLY UNDERSTOOD. WITH AN INCREASE IN COMORBIDITIES...

TODAY, BECAUSE OF THE VARIETY OF WOUNDS, A WIDE RANGE OF WOUND DRESSINGS PRODUCE WITH DIFFERENT OBJECTIVES. ONE OF THE WOUND DRESSING, THAT SKIN TISSUE ENGINEERING SCIENTISTS WERE CONCERNED, IS THE USE OF ANIMAL TISSUE MODELS AS BIOLOGICAL DRESSING FOR WOUND HEALING...

BACKGROUND: WHEN THE SKIN AS A PHYSICAL BARRIER IS DAMAGED, PATHOGENS HAVE A DIRECT ROUTE TO INFILTRATE THE BODY, POSSIBLY RESULTING IN INFECTION. THEREFORE OUR TASK IS PRIMARILY TREATMENT THE WOUNDS TO PREVENT THE INFECTIONS AND STIMULATE THE SKIN TO REPAIR IS IN SECOND GRADE. NOWADAYS BIODEGRADABLE MATERIALS ARE GAINING EXTENSIVE ATTENTION IN THE FIELD OF SOFT TISSUE ENGINEERING...

BACKGROUND: DIABETES IS A CHRONIC DISEASE. LIFESTYLE AND DEMOGRAPHIC CHANGES HAVE RESULTED IN MUCH MORE DIABETICS WITH INCREASING MORBIDITY AND MORTALITY.160 YEARS AGO, CALVI AND HODGKIN DESCRIBED THE COMPLICATION OF DIABETIC FOOT ULCERS...

SHORTEN TIME THE HEALING PERIOD WOUNDS OF SURGERY HAS MANY ADVANTAGES. WOUND HEALING IS A COMPLEX PHENOMENON, BUT ORGANIZED. IDENTIFIED AND COORDINATED PROCESSES SUCH AS RECONSTRUCTION, MOVEMENT AND PROLIFERATION OF PARENCHYMAL CELLS AND CONNECTIVE TISSUE CELLS AND REBUILD TISSUES ARE INVOLVED. THIS STUDY AIMED TO INVESTIGATE THE EFFECTS OF LOW-LEVEL LASER WITH A WAVELENGTH OF 635 NM EXCITATION PROCESSES AND ACCELERATE WOUND HEALING AFTER AMPUTATION WAS PERFORMED.

BACKGROUND: BEDSORE IS A SERIOUS COMPLICATION FORE HOSPITALIZED PATIENTS. PREVENTION OF BEDSORE IS CONSIDERED AS A PRIORITY IN ACUTE AND LONG-TERM CARE IN INTENSIVE CARE UNITS. IT IS PURPOSE PATTERN QUALITY NURSING CARE. THIS STUDY AIMED TO DETERMINE THE EFFECT OF NURSE’S ROLE IN PREVENTION OF PRESSURE SORE IN INTENSIVE CARE UNITS.

DIABETES IS AN EVER INCREASING PHENOMENON IN THE WORLD.OF DIABETIC PATIENTS, IT IS ACCEPTED THAT 15-25% OF THESE PATIENTS WILL DEVELOP A DIABETIC FOOT ULCER1 PATIENTS WITH DIABETES ARE 22 TIMES MORE LIKELY TO UNDERGO A NON- TRAUMATIC AMPUTATION THAN AN INDIVIDUAL WITHOUT DIABETES2...

DELAYS IN BURN WOUND CLOSURE WORSEN A PATIENT’S SUSCEPTIBILITY TO INFECTION, PROLONG PAIN, INCREASE THE TOTAL NUMBER OF OPERATIVE PROCEDURES, INCREASE THE INCIDENCE OF HYPERTROPHIC SCARRING, AND LENGTHEN HOSPITAL STAYS.

BACKGROUND: ALTHOUGH BURN INJURY ARE COMMON, TREATMENT FOR DISABLING CONDITION REMAIN LIMITED AND SEVERE BURNS PROVIDES IRREPARABLE EFFECTS ON THE AFFECTED PATIENT. EVIDENCE DEMONSTRATE THAT BONE MARROW MESENCHYMAL STEM CELLS (BMSC) ARE USEFUL FOR ACCELERATE BURN HEALING. AS WELL AS SEVERAL STUDY SHOW THAT STIMULATED BONE MARROW MESENCHYMAL STEM CELLS (SBMSC) WITH LPS OR POLY-I-C HAS MORE THERAPEUTIC POTENTIAL THAN UNSTIMULATED CELL TO ACCELERATE TISSUE WOUND HEALING.THE AIM OF THIS STUDY WAS TO INVESTIGATED THE EFFECTS OF SBMSC WITH COMPOUND LPS AND POLY-I-C AT THE SAME TIME ON BURN HEALING AND COMPARED WITH UNSTIMULATED BMSC GROUP.

THE RISE IN THE INCIDENCE OF OBESITY AND DIABETES HAS INCREASED THE BURDEN OF TREATING CHRONIC WOUNDS.BURN INJURIES ALSO AFFECT 11 MILLION PEOPLE WORLDWIDE ANNUALLY. IN ADDITION, POSTSURGICAL WOUND CARES ARE NOT COST EFFECTIVE FOR HEALTHCARE SYSTEM. ALTHOUGH CONVENTIONAL SPLIT-THICKNESS AUTOLOGOUS SKIN GRAFTS (STSGS) ARE STILL THE GOLD STANDARD OF CARE FOR BURN TREATMENT, FINDING AN ALTERNATIVE APPROACH IS ESSENTIAL DUE TO THE DISADVANTAGES OF SKIN AUTOGRAFTS SUCH AS LIMITED HEALTHY DONOR SITES IN EXTENSIVE BURNS AND DONOR-SITE MORBIDITY.

LYMPHEMEA IS AN ACCUMULATION OF PROTEIN RICH FLUID IN INTERSTITIAL TISSUE. IT IS ONE THE MOST COMMON PROBLEM WHICH MAY SOMETIMES PRESENT PRIMARY OR HEREDITARY DUE TO INSUFFICIENCY OR LACK OF LYMPH NODES OR LYMPH VESSELS. THE MOST COMMON FORM OF LYMPHEDEMA OCCURS SECONDARY TO SURGERY OR INJURIES TO LYMPH PATHWAYS.

BACKGROUND: THE AIM OF THIS STUDY WAS TO INVESTIGATE EFFECTIVENESS OF BIOACTIVE WOUND DRESSING FOR TREATING DIABETIC FOOT ULCERS (DFU)...

HUMAN INFECTION WITH LEISHMANIA PARASITES WHICH PRESENTS SEVERAL DIFFERENT CLINICAL FORMS OF DISEASES; CUTANEOUS LEISHMANIASIS (CL), THE MOST COMMON FORM OF THE DISEASE AND VISCERAL LEISHMANIASIS (VL) WHICH IS THE FETAL FORM OF THE DISEASE...

WITH THE CONTEMPORARY SCHOOLS OF THOUGHT IN MEDICINE AND MEDICAL - RELATED FIELDS, IN WHICH REPLACEMENT METHODS ARE BEING GRADUALLY SUBSTITUTED BY REGENERATIVE APPROACHES, NEW CONCEPTS IN DENTISTRY SUCH AS “VITAL PULP THERAPY” AND “ENDODONTIC REGENERATION PROTOCOL (ERP) ”WITH PROMISING RESULTS AND OUTCOMES HAVE RECENTLY BEEN TAKEN INTO ACCOUNT.

BOTULINUM TOXIN (BT) IS THE EXOTOXIN OF CLOSTRIDIUM BOTULINUM; BOTULINUM TOXIN TYPE A (BTA) HAS BECOME ONE OF THE MOST FREQUENTLY REQUESTED PRODUCTS IN COSMETIC REJUVENATION. BOTULINUM TOXIN IS COMMONLY USED IN NEUROLOGY, ORTHOPEDIC AND PLASTIC SURGERY TO ALLEVIATE MUSCLE CONTRACTIONS AND SPASMS.IT EXERTS ITS EFFECTS BY REVERSIBLY BLOCKING THE RELEASE OF ACETYLCHOLINE FROM THE PRESYNAPTIC TERMINAL AT NEUROMUSCULAR JUNCTION.

BACKGROUND: PRESSURE ULCERS ARE INJURIES OF THE SKIN AS A COMMON CLINICAL COMPLICATION, ESPECIALLY AMONG HOSPITALIZED PEOPLE IN DIFFERENT HEALTH CONTEXTS. IT NORMALLY OCCURS ON BONY PROMINENCE SITES AND MAINLY DUE TO LIMITED MOBILITY AND PHYSICAL ACTIVITIES. PRESSURE ULCERS ARE SERIOUS PUBLIC HEALTH ISSUES AND CAN BE COMPLICATED BY PAIN AND INFECTIONS LEADING TO HIGH ECONOMIC BURDEN. FROM IRANIAN TRADITIONAL MEDICINE POINT OF VIEW, ULCERS ARE DIVIDED INTO DIFFERENT TYPES AND HERBAL REMEDIES ARE PROVIDED ACCORDINGLY. THIS STUDY HAS DISCUSSED TREATMENT OF PRESSURE FROM IRANIAN TRADITION MEDICINE POINT OF VIEW. ALSO, IT HAS COMPARED THE RESULTS WITH THOSE OBTAINED IN MODERN MEDICINE.

STEM CELL BIOLOGY HAS GAINED REMARKABLE INTEREST IN RECENT YEARS, DRIVEN BY THE HOPE OF FINDING CURES FOR NUMEROUS DISEASES INCLUDING SKIN WOUND HEALING THROUGH TRANSPLANTATION MEDICINE...

AS A NEW BIOMATERIAL, POLYETHER-ETHER-KETONE (PEEK) HAS GAINED WIDESPREAD ACCEPTANCE AS A HIGHSTRENGTH POLYMER USED IN HARD AND SOFT TISSUE RECONSTRUCTIONS, WITH FAVORABLE IMAGING COMPATIBILITY AND STIFFNESS THAT CLOSELY MATCHES BONE. THE ULTIMATE GOAL OF MOST MEDICAL IMPLANTS IS TO RESTORE IMPAIRED BIOLOGICAL FUNCTION AND ACHIEVE FUNCTIONAL INTEGRATION WITH THE BODY. SEVERAL POROUS POLYMERS AND OTHER TISSUE ENGINEERED SCAFFOLDS HAVE MADE ADVANCES IN THIS REGARD, HOWEVER SIMILAR SOLUTIONS IN HIGH LOADBEARING ORTHOPEDIC ENVIRONMENTS REMAIN ELUSIVE IN CLINICALLY ADOPTED BIOMATERIALS.

FROM PRECISE AESTHETIC WORK TO MOST CHALLENGING RECONSTRUCTIVE CASES, PREVENTING AND TREATING PROBLEM SCARS ARE KEY TO PATIENT SATISFACTION AND GOOD SURGICAL OUTCOMES.UNDERSTANDING SCARRING DETERMINES OUR SURGICAL PLANNING, OUR APPROACH, AND OUR TECHNIQUE. MINIMIZING SCARRING CAN LEAD TO BOTH IMPROVED FORM AND FUNCTION. IN THIS PRESENTATION I TRY TO SHARE MY EXPERIENCE ON SCAR MANAGEMENT WITH COLLEAGUES. MY TALK INCLUDES; ASSESSING SCARS, SCAR BIOLOGY, CONDITIONS OF EXCESSIVE SCARRING, LIKE HYPERTROPHIC SCAR AND KELOID...

BACKGROUND: ETHNOMEDICINAL PLANTS HAVE BEEN IDENTIFIED AND PRESCRIBED ALL OVER HUMAN HISTORY. PLANTS MAKE MANY CHEMICAL COMPOUNDS THAT ARE FOR BIOLOGICAL FUNCTIONS, INCLUDING WOUND HEALING, AND DEFENCE AGAINST FUNGI AND BACTERIA.

BACKGROUND: BURNS INJURIES, SPECIALLY SEVER ONES, HAVE AN ADVERSE EFFECT ON PEOPLE`S PERSONAL AND SOCIAL LIFE. INCREASING EVIDENCE DEMONSTRATE THAT BONE MARROW MESENCHYMAL STEM CELLS ARE USEFUL FOR ACCELERATE BURN HEALING. IN THESE STUDY EFFECTS OF STIMULATED BONE MARROW MESENCHYMAL STEM CELLS WITH LPS AND POLY-I-C WERE ASSESSED ON BURN HEALING AND COMPARED WITH CONTROL GROUP.

BACKGROUND: IN THE 1980S, TISSUE ENGINEERED SKIN SUBSTITUTES EMERGED BECAUSE OF THE CRITICAL NEED FOR EARLY COVERAGE OF EXTENSIVE BURN INJURIES IN PATIENTS WITH INSUFFICIENT SOURCES OF AUTOLOGOUS SKIN GRAFTING AND THEY HAVE RECENTLY BECOME A SUITABLE AND HIGHLY PRACTICAL ALTERNATIVE OF IT...

WOUND MANAGEMENT IS A COMPLEX PROCESS WHICH HAS A VERY LARGE SOCIAL AND HEALTH BURDEN ON THE COMMUNITY AS WELL AS INDIVIDUALS. THERE ARE LIMITED EVIDENCE-BASED DOCUMENTS FOR THE ROLE OF NUTRITION IN WOUND HEALING AND WOUND CARE PRACTICES. HOWEVER, WE KNOW THAT NUTRITION PLAYS AN ESSENTIAL ROLE IN THE MANAGEMENT OF PATIENTS WITH WOUNDS AND DECREASING THE MORTALITY AND MORBIDITY ASSOCIATED WITH CHRONIC WOUNDS. ADEQUATE NUTRITION CAN IMPROVE IMMUNE FUNCTION, COLLAGEN CREATION, AND WOUND TENSILE STRENGTH THAT ALLOW PROGRESSION THROUGH STAGES OF WOUND HEALING...

ONE OF THE MALIGNANT SIDE EFFECTS OF RADIATION IN TREATMENT OF MAXILOFACIAL MALIGNANCIES IS OSTHEORADIONECROSIS.

PHOTODYNAMIC THERAPY (PDT) IS AN EMERGING, NON-INVASIVE THERAPEUTIC STRATEGY THAT INVOLVES PHOTOSENSITIZER (PS) DRUGS AND EXTERNAL LIGHT FOR THE TREATMENT OF DISEASES. THE PRINCIPAL MEDICAL APPLICATION DURING THE LAST CENTURY WAS IN CANCER THERAPY BUT...

BACKGROUND: WE AIMED TO EVALUATE THE EFFICACY OF BIOIMPLANT DRESSING IN COMPARISON WITH WET DRESSING IN DIABETIC PATIENTS WITH FOOT ULCERS...

BACKGROUND: ALOE VERA AS ONE OF THE HEALING WAYS HAVE SUGGESTED THAT MAY HELP ACCELERATE THE WOUND HEALING PROCESS. ALOE VERA IS A TROPICAL PLANT BELONGING TO THE LILIACEAE FAMILY. ALOE GEL OPERATES BY FORMING A PROTECTIVE COATING ON THE AFFECTED AREAS, HENCE SPEEDING UP THE HEALING PROCESS. THIS STUDY WAS DONE FOR DETERMINING EFFECTIVENESS ALOE VERA ON HEALING OF DIFFERENT TYPES OF WOUNDS.

SKIN IS A LARGE ORGAN IN BODY WITH RENEWAL ABILITY IN MILD LEVELS BUT NOT IN HARD INJURIES CONDITIONS.SO CURRENT METHODS AMONG ALLOGRAPHS AND AUTOGRAPHS HELP PATIENTS TO TREAT; THESE METHODS HAVE SOME DISADVANTAGES AND ADVERSE EFFECTS WHICH INDUCED TO APPLY TISSUE ENGINEERING METHODS...