P233- EFFECTS OF A549-CONDITION MEDIUM ON MOUSE EMBRYONIC STEM CELLS DIFFERENTIATION INTO ALVEOLAR EPITHELIAL TYPE II CELLS

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Mokhber Dezfouli Mohammad Reza; Sadeghian Chaleshtori Sirous; BAHARVAND HOSSEIN; TAHAMTANI YASER; Yadollahi Shokufe

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Seminar Paper

Paper Information

Seminar: INTERNATIONAL CONGRESS ON STEM CELLS AND REGENERATIVE MEDICINE
Year:2015 | Issue:1

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Title

P233- EFFECTS OF A549-CONDITION MEDIUM ON MOUSE EMBRYONIC STEM CELLS DIFFERENTIATION INTO ALVEOLAR EPITHELIAL TYPE II CELLS

Author(s)

Mokhber Dezfouli Mohammad Reza | Sadeghian Chaleshtori Sirous | BAHARVAND HOSSEIN | TAHAMTANI YASER | Yadollahi Shokufe

Keywords

A549-C.M

AETII CELLS

MESCS

DIFFERENTIATION

Abstract

OBJECTIVE: A549 CELLS ARE ADENOCARCINOMIC HUMAN ALVEOLAR BASAL EPITHELIAL CELLS. THESE CELLS ARE RESPONSIBLE FOR THE DIFFUSION OF SOME SUBSTANCES, SUCH AS WATER AND ELECTROLYTES, ACROSS THE ALVEOLI OF LUNGS. A549 CELL LINE ARE WIDELY USED AS AN IN VITRO MODEL FOR A ALVEOLAR EPITHELIAL TYPE II (AETII) CELL MODEL FOR DRUG METABOLISM AND AS A TRANSFECTION HOST. THE MAIN FUNCTIONS OF AETII CELLS, INCLUDING THE SYNTHESIS AND SECRETION OF SURFACTANTS (A MIXTURE OF PROTEINS AND LIPIDS WHICH REDUCES SURFACE TENSION AND PREVENTING COLLAPSE OF THE ALVEOLUS), HYPERPLASIA IN REACTION TO ALVEOLAR EPITHELIAL INJURY AND ACT AS PROGENITOR CELLS FOR AETI CELLS (WHICH ARE ESSENTIAL FOR GAS EXCHANGE), THUS BEING ABLE TO RENEW THE ALVEOLAR EPITHELIUM. THE AIM OF THE STUDY WAS TO EVALUATE THE EFFECTS OF THE A549-CONDITION MEDIUM (A549-C.M) ON THE AETII CELLS DIFFERENTIATION FROM MOUSE EMBRYONIC STEM CELLS (MESCS)...

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APA: Copy

Mokhber Dezfouli, Mohammad Reza, Sadeghian Chaleshtori, Sirous, BAHARVAND, HOSSEIN, TAHAMTANI, YASER, & Yadollahi, Shokufe. (2015). P233- EFFECTS OF A549-CONDITION MEDIUM ON MOUSE EMBRYONIC STEM CELLS DIFFERENTIATION INTO ALVEOLAR EPITHELIAL TYPE II CELLS. INTERNATIONAL CONGRESS ON STEM CELLS AND REGENERATIVE MEDICINE. SID. https://sid.ir/paper/923400/en

Vancouver: Copy

Mokhber Dezfouli Mohammad Reza, Sadeghian Chaleshtori Sirous, BAHARVAND HOSSEIN, TAHAMTANI YASER, Yadollahi Shokufe. P233- EFFECTS OF A549-CONDITION MEDIUM ON MOUSE EMBRYONIC STEM CELLS DIFFERENTIATION INTO ALVEOLAR EPITHELIAL TYPE II CELLS. 2015. Available from: https://sid.ir/paper/923400/en

IEEE: Copy

Mohammad Reza Mokhber Dezfouli, Sirous Sadeghian Chaleshtori, HOSSEIN BAHARVAND, YASER TAHAMTANI, and Shokufe Yadollahi, “P233- EFFECTS OF A549-CONDITION MEDIUM ON MOUSE EMBRYONIC STEM CELLS DIFFERENTIATION INTO ALVEOLAR EPITHELIAL TYPE II CELLS,” presented at the INTERNATIONAL CONGRESS ON STEM CELLS AND REGENERATIVE MEDICINE. 2015, [Online]. Available: https://sid.ir/paper/923400/en

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