Introduction: key roles in learning, memory and attention in humans is long, so that people are constantly seeking ways Which strengthens memory and reduce its deficit to pull up The effects of Nigella sativa extract on learning and memory in adult male rats was studied.Material and METHODS: This was an experimental study. For this 40 sar purpose, adult male Wistar rats weighing 220-180 g were divided into 5 groups of 8 And control groups, control). (The control group received nothing, 1/.0 ad lib controls ml normal saline gavage, is administered). Experimental groups 1, 2 3 daily doses of 100, 200 and 400 mg kg body weight extract of Nigella 17 days of receiving And then after 12 day get started learning extracts and extract operation is performed simultaneously with training and probe trial on day 18 without prescription extract is Barnes Maze taken from animals. The study was time delay for the purpose of this to evaluate the error number..Rresults: The results of this study showed that Nigella sativa significantly compared to the control groups Thereby increasing the learning and spatial memory.: (P<0.05). Conclusions: The results demonstrated that administration of Nigella sativa seed extract, oleic acid and linoleic acid antioxidant inflammation due to spatial memory is enhanced.