The aim of this research is to design an strategic model of social innovation in the Islamic Republic of Iran. This research, in terms of purpose, is developmental-functional, and in terms of data collection is a survey. The statistical populations includes 25 experts with practical experience, scientific management and innovation in the field of social affairs in the Islamic Republic of Iran which were selected by targeted and snowball sampling method. After conducting exploratory studies and consulting the experts, eight dimensions of the macro pattern were extracted. Using the software "Smart PLS" factor analysis was performed. In order to determine the relationship between dimensions and ranking them, Interpretive Structural Modeling was used. The results showed that based on the criteria of "Conductivity impact" and " Dependence", "Foundation's values", as the key independent variable are at the fourth level, the "Social Climate", at the third level, the dimensions of "Structures and institutions", "Resources" and "Policy framework", as Joiner variables at the second level, and finally "Content", "Process" and "Governance and capacity building", as the dependent variables are at the first level.