Diabetes is a type of body metabolic derangement that leads to high blood sugar level following low action or lack of insulin. Several type of antidiabetic drugs are used for treatment of high blood sugar level. But due to lack of effective treatment, dietary modification and other alternative intervention is fundamental to successful treatment of diabetes whether it is type I or II. Epidemiological evidence indicates strong correlation between the processed food diet habits and incidence of diabetes. However the reestablishing a traditional diet and lifestyle as well as alternative treatment of diabetes may reduce the incidence and late complication of type II diabetes. Herbal preparation are used by diabetic patients in all societies even in industrialized countries especially among unsuccessfully treated patients and those who are candidate for insulin therapy. As most of the physicians advice their patients not to use herbal medicine, the diabetic patients will use it without knowledge of their physicians. This type of herbal therapy may lead to drug interaction or false and unstable blood glucose level monitoring. The present review covers advance knowledge of herbal medicine including: Allium cepa L., Allium sativum L.Mamordica charantia L., Gymnema sylvestre L., Trigonella foenum graecum L., Atriplex halimus L., Vaccinium myrtillus L., Ginkgo biloba L., Silybum marianum L. Gaertn.,Citrullus colocynthis (L.) Schrad, Securigera securidaca L. Camellia sinensis L. and some flavanoids in the management of diabetes.