The theoretical frameworks of geopolitical knowledge have always been based on territorial realities, and the rational approaches been employed in geopolitical research. Clearly, the main concerns of the scholars in this field have been the identification of the key geographical regions of the world, and the effort for building models of competition between the world powers in these geographical spheres. Undoubtedly, the geopolitical rivalries of the global powers have revolved around gaining access to the existing assets and resources in different geopolitical regions. In order to understand the patterns of the world power competition, and to make predictions about these rivalries, there is a need for identifying the world strategic regions, their attributes and the geographical passages to these regions. The understanding of the important characteristics of the vital strategic regions of the world will facilitate the task of predicting events and incidences in the interstate relations and at the system level. Using an analytical approach, the authors have brought together the historical post-Cold War events and the realities of the geographical space of Eurasia, in an attempt to explain the theoretical models and the vital attributes of strategic regions in this supercontinent.