Aims: Evidence-based nursing guidelines can significantly improve the quality of nursing care. A key prerequisite for improving care quality is quality assessment. Meanwhile, a key indicator of healthcare quality is the quality of nursing care. The aim of this study was to investigate the effects of implementing evidence-based guidelines on the quality of nursing care provided to patients with angina pectoris.Methods: This pretest-posttest clinical trial was conducted in 2014 on 76 patients in Khatam Al-Anbia hospital, Gonbad-e Kavoos city, Iran. A standardized questionnaire was used for assessing the quality of nursing care standards both before and after educating evidence-based nursing guidelines. The SPSS15 was used for conducting statistical tests such as the paired- and independent-samples t and the Chi-square.Results: Before the study, the means of documentation quality in four areas of nursing diagnosis, care planning, implementation, and evaluation were respectively 0.94 (0.19), 0.63 (0.10), 11.57 (0.23), and 2.57 (0.18), and. After the study, these values increased to 3.2 (0.14), 3.52 (0.17), 15.36 (0.22), and 5.7 (0.23), respectively. The differences between the pretest and posttest readings were statistically significant (p<0.001).Conclusions: Given the significant effects of implementing evidence-based nursing guidelines on the quality of nursing care standards, educational managers of hospitals need to develop effective strategies for facilitating evidence-based nursing practice.