"Multilateral sanctions" approach stresses the broad economic, military, social, transport, and the United States of America against Iran in the present paper. In this paper, the analytical method and using library resources, the Internet, and has been prepared, In response to the question paper, the main hypothesis of this paper states, " United States of America with the best strategy to boycott boycott, attempts to With the expansion of sanctions against Iran as much as possible, The lives of people living with paralysis as the fulcrum, Tap into the power of the Iranian people by fomenting protests, Iran's behavior will change constantly through sanctions". The findings of this study show that: 1. America sanctions against Iran's efforts to describe the United States Global Leadership Crisis Management and; 2. Not only is the country's nuclear negotiations with Iran now, sanctions on a stage and will be discontinued but even if the settlement of the nuclear issue will attempt to boycott boycott strategy, with changes of direction and purpose of sanctions to impose new sanctions on the Islamic Republic's new demands. This paper concludes that, America's policy interpretation sanctions against Iran, along with other developments in the area of conflict between Russia and America, Dash appearance is necessary; also, Government and government-wide efforts to increase public awareness about the strategy of identifying and sanctioning the United States embargo against Iran to be considered.