International political economy is considered one of the social science disciplines. This field of study, which has received serious attention in the West, benefited itself from various fields of social sciences for better understanding of the complex problems of interdependency of the world community. Politics, economy, sociology, anthropology, philosophy, comparative politics, and international organizations are all contributing to the understanding of international political economy; as such international political economy is a multidisciplinary field of study which involves multivariable and dimensions. It is tried in this article to use all levels of analysis including individual, national and international levels in theoretical and practical explanation of international political economy. In addition to this, it is also tried to assess, theoretically and pragmatically, the USA and Chinese relations so that the theoretical and practical approaches jointly make comprehension attainability of international political economy easier.