The purpose of this research is to study the method of distribution of thermal models of land surface and the normalized indicator of vegetation and the relationship between these two variables in the cold and hot seasons in Isfahan city as one of the most important population centers in Iran. In line with this objective, employing the four images of the Landsat TM sensor, the land surface temperature and the normalized Index of vegetation in a 19-year time span was made in the dates of January 7, 1991, June 16, 1991, December 29, 2010 and July 4, 2010. The results of the research showed that: On 7 January, 1991, the minimum temperature of-1.1 centigrade, the maximum temperature of 16 centigrade with an average of 5.1 and standard deviation of 1.4 were calculated. On 16 June, 1991, the minimum temperature of 16, the maximum temperature of 33 centigrade with an average of 28 centigrade and standard deviation of 3, On 4 June, 2010, the minimum temperature of 18, the maximum temperature of 37, with an average of 29 centigrade and standard deviation of 3.2, On 29 December, 2010, the minimum temperature of -3.6, the maximum temperature of 19, with an average of 7.7 centigrade and standard deviation of 3.2 were calculated. Also, the index minimum On 7 January, 1991 of -0.96 and its maximum of 0.78 with an standard deviation of 0.1 and On 16 June, 1991, the minimum index of -0.36, the maximum of 0.66 and the standard deviation of 0.14, On 4 June, 2010, the minimum index of -0.23, the maximum of 0.68 and the standard deviation 0.11 and on 29 December, 2010, the minimum index of -0.4, the maximum of 0.56 and the standard deviation of 0.066 were calculated. The dispersion of the hot temperature range in the regions of 5, 6 and 13 and in the cold period of the year and the hot temperature range in the regions of 6 and 5 and cold in the peripheral regions of Zayandeh Rood (River) in the hot period of the year is observable.