The idea of guardianship is in an indispensible relationship with the theory of perfect man in mysticism, because for mystics human being is comprehensive in the total universal order and builds up the ultimate reflection of divine attributes.Of course, this fact is embedded within the whole human beings in a concealed and unknown way, and every mankind holds the overall the perfect divine manifestations out of which it is only cognitivity and guardianship followers who are deserved to have the attributes actively.Elder mystics believe that guardianship constitutes prophetic mission and prophetic mission in turn makes up the apparent guardianship. In other words, it is by the manifestation of guardianship in the intuitive universe and the source of existence that prophetic mission is constituted, so is caliphate the product of guardianship. In addition, one of the most important points in terms of guardianship, especially in the eyes of mystics, is the "final guardianship" that is still the battle field for the experts and enthusiasts of mysticism.The writer tries in addition to briefly indicate the approach devised by a group of pseudo mystics toward guardianship, explaining the facts of guardianship in mysticism and its relation with prophetic mission, study the attitudes of cognition followers according to some religious verses and traditions, especially Imam Khomeini and Ibn Arabi who have achieved the acme of revelation and spiritual diligence and spirituality of the self, and later makes the conclusion out of their mystical ideas as much as possible.