Background and Objective: In this age that is the age of knowledge, attracting knowledge workers among the issues is that ignoring it destroy the organization, also slowly bring growth and development of the country. The objective of resent research is to identify the effective location factors on attracting knowledge workers in the public sector of Iran.Methods: This study is a descriptive- correlation research that has been conducted through a survey. Also, this study is in terms of the aim the development- applied research. The study population consisted of all staffs in ministry of science, research and technology that their number is 417 persons, and all of them were selected as volume of sample. The data gathering tool was the questionnaires of the assessment of condition knowledge-axial, effective location factors on attracting knowledge workers and attracting knowledge workers that the validity and reliability of the questionnaires have been approved, and descriptive and inferential statistics have been used to analyze the data.Findings: The results of enter multiple regression confirmed the suggested model of research, also indicated that technical infrastructure, amenities and entertainment, social and economic security, social services, social equality, population diversity, civil liberties, quality of urban architecture and environmental, cost of living index, housing, and conditions of labour market are including effective location factors on attracting knowledge workers in the public sector of Iran, and among the factors, social equality have had the most impact on attracting knowledge workers.Conclusion: Given that the effective location factors on attracting knowledge workers in the public sector of Iran include technical infrastructure, amenities and entertainment, social and economic security, social services, social equality, population diversity, civil liberties, quality of urban architecture and environmental, cost of living index, housing, and conditions of labour market, therefore executive officers should realiz each of effective location factors on attracting knowledge workers via the development and implementation of appropriate policies and programs.