Introduction: Injury to muscles, tendons, ligaments, joints, nerves, blood vessels and soft tissues lead to musculoskeletal disorders. Type of work, the rate of repetition, severity and duration of work are risk factors for musculoskeletal disorders. Food plants contain repetitive motions so it is necessary to study the prevalence of musculoskeletal disorders in this study.Methods: This study is a descriptive- analytical study to investigate the prevalence of musculoskeletal disorders in the one of the food manufacturing plans. Therefore, 200 workers in this industry were examined. In order to determine the prevalence of musculoskeletal disorders and symptoms Nordic questionnaire was used and to identify different body parts affected, body map questionnaire was used. Data was analyzed using SPSS (Ver. 18).Results: The most common symptoms of patients were related to low back. Chi square test showed a significant relationship between sex and prevalence of symptoms in the areas of back, shoulder and elbow of workers during the past 12 months (P<0.05). But in the neck, thighs, knees and feet we did not see any significant difference.Conclusion: Sex is a risk factor for development musculoskeletal disorders, so as the prevalence of symptoms in women was more than men.