Psychodynamic school is sensitive to socio-cultural factors. Namely its theoretical and practical applicability in non-western cultures had been always arguable. The aim of this study is to identify compatibilities and incompatibilities of psychodynamics in Iran. Theoretical applicability considers based on literature review and experts' references. Practical applicability will design based on facilities, barriers, compatibilities and incompatibilities, adjustments and suggestions that psychodynamic psychotherapists had in their practices with Iranian samples. According to Grounded theory methodology developed through codification process showed that applicability of psychodymics in Iran can be demonstrated by three connected elements. Executive mechanisms such as systematic vicious cycles, adjustments, preparatory items and the best selected approaches could determine applicability of psychodynamics in Iran, on the one hand, and redefining limits of psychodynamics and contextual changings in Iran, on the other hand. Although this school is an opportunity to investigation psychic dymics in Iran, but considering new approaches such as assimilative self, decentered self or median Islamic orientation could increase its flexibility, applicability and coverage faced with psychic dynamics in Iran.