Today, with the Iranian academic system, the industry and lack of conformity of academic functions to the needs of external society on the one hand, and the lack of financial resources on the other hand, has faced a number of challenges for the academic systems. The disruption of the academic system of the industry, in addition to waste of resources also has the country's persistence in achieving development. Therefore, the aim of present research is to design an entrepreneurial university model at Tehran University. In the methodology section, qualitative exploratory and content analysis methods have been used. In the first part, interviews were conducted with purposeful sampling and semi-structured interview with 8 faculty members of Faculty of Entrepreneurship of Tehran University and 4 managers of companies in Science and Technology Park. In the content analysis section, internal and external articles in the territory of the University of Entrepreneur were selected from databases after searching in the time period (1385-1397) (1998-2015), which resulted in a total analysis of 30 articles after the publication of the papers. After reading their main concepts, they were analyzed and classified. Based on the findings of this research, a total of 184 concepts were extracted and in the components of the University of Entrepreneurs altogether, 11 core categories, 30 sub categories and 88 concepts were considered. In the factors affecting the entrepreneurial university; 4 axial categories, 12 subcategories and 31 concepts were extracted and categorized and then depicted in the schematic model.